Results 71 to 80 of about 706 (177)

Case Report of Acute Kidney Injury in Organophosphorus Poisoning and Potential Association with Oxime Use [PDF]

Asia Pacific Journal of Medical Toxicology
Introduction: Organophosphorus poisoning (OP) represents a significant public health issue, particularly in developing countries, due to its extensive availability and high toxicity.
Nourhan Saeed, Rania Youssef, Maram Mostafa   +2 more
doaj   +1 more source

Repetitive obidoxime treatment induced increase of red blood cell acetylcholinesterase activity even in a late phase of a severe methamidophos poisoning: A case report.

, 2016
Accidental self-poisoning or deliberate use in suicidal intent of organophosphorus pesticides (OPP), which are widely used in agriculture, represent a health problem worldwide. Symptoms of poisoning are characterized by acute cholinergic crisis caused by
Steinritz, Dirk;Eyer, Florian;Worek, Franz;Thiermann, Horst;John, Harald
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Percutaneous exposure to the nerve agent VX: Efficacy of combined atropine, obidoxime and diazepam treatment

, 2010
The nerve agent VX is most likely to enter the body via liquid contamination of the skin. After percutaneous exposure, the slow uptake into the blood, and its slow elimination result in toxic levels in plasma for a period of several hours.
Joosen, M.J.A., Marcel J. van der Schans, Herman P.M. van Helden, Schans, M.J. van der, Marloes J.A. Joosen, Helden, H.P.M. van   +5 more
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Efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate: comparison with pralidoxime, obidoxime, trimedoxime, methoxime, and HI-6

, 2009
Introduction. The new K-oximes, K-27 [1-(4-hydroxyimino-methylpyridinium)-4-(4-carbamoylpyridinium) propane dibromide] and K-48 [1-(4-hydroxyimino-methylpyridinium)-4-(4-carbamoylpyridinium) butane dibromide], show good in vitro efficacy in protecting ...
Hasan, M. Y., Kuca, K., Schmitt, A., Nurulain, S. M., Petroianu, Georg A., Lorke, D. E.   +5 more
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Avanços sobre a neurotoxicidade induzida pelo pesticida organofosforado malation em modelos experimentais com camundongos [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasO pesticida organofosforado (OF) Malation é um composto utilizado como inseticida em áreas urbanas e rurais. Sabe-se
Silva, Aline Preve da
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Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model

, 2021
Nerve agent exposure is generally treated by an antidote formulation composed of a muscarinic antagonist, atropine sulfate (ATR), and a reactivator of acetylcholinesterase (AChE) such as pralidoxime, obidoxime (OBI), methoxime, trimedoxime or HI-6 and an
Groningen, T. van, Barry, J., Kentrop, J., Bohnert, S., Cornelissen, A.S., Joosen, M.J.A., Klaassen, S.D., Cochrane, L., Savransky, V.   +8 more
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In Vitro Ability of Currently Available Oximes to Reactivate Organophosphate Pesticide-Inhibited Human Acetylcholinesterase and Butyrylcholinesterase

, 2011
We have in vitro tested the ability of common, commercially available, cholinesterase reactivators (pralidoxime, obidoxime, methoxime, trimedoxime and HI-6) to reactivate human acetylcholinesterase (AChE), inhibited by five structurally different ...
Daniel Jun, Lucie Musilova, Kamil Kuca, Kamil Musilek   +3 more
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Reactivation of Human Acetylcholinesterase and Butyrylcholinesterase Inhibited by Leptophos-Oxon with Different Oxime Reactivators in Vitro

, 2010
We have evaluated in vitro the potency of 23 oximes to reactivate human erythrocyte acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BChE) inhibited by racemic leptophos-oxon (O-[4-bromo-2,5-dichlorophenyl]-O-methyl phenyl-phosphonate), a ...
Miroslav Pohanka, Young-Sik Jung, Daniel Jun, Pavel Bostik, Lucie Musilova, Kamil Kuca   +5 more
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Einfluss des Paraoxonase-Phänotyps auf die Abbaugeschwindigkeit hochtoxischer Phosphoryloxime [PDF]

, 2007
Die Fähigkeit der meisten aktiven Pyridinium-4-Aldoxime, wie Obidoxim und Trimedoxime, zur Reaktivierung phosphorylierter Acetylcholinesterase (AChE) ist noch nicht vollständig untersucht, da es zur unvermeidbaren Bildung von Phosphoryloximen (POX) kommt,
Stenzel, Jochen
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Testing of antidotes for organophosphorus compounds: Experimental procedures and clinical reality.

, 2007
According to current knowledge, inhibition of acetylcholinesterase (AChE) is a very important toxic action of organphosphorus compounds (OP). Hence, it is obvious to follow the AChE activity in order to quantify the degree of inhibition and to assess ...
Eyer, P;Szinicz, L;Thiermann, H;Worek, F;Zilker, T
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