Acta Medica, 2001 1. The influence of anticholinergic drugs (atropine, benactyzine, biperiden) on the efficacy of monopyridinium and bispyridinium oximes (HI-6, BI-6, obidoxime, pralidoxime, methoxime) on soman-induced supralethal poisoning was studied in mice. 2.
Jiří Kassa
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Management of Treatment and Prevention of Acute OP Pesticide Poisoning by Medical Informatics, Telemedicine and Nanomedicine [PDF]
, 2013 Acute organophosphorous pesticide (OP) poisoning kills a lot of people each year. Treatment of acute OP poisoning is of very difficult task and is a time taking event.
Anurag Singh Chauhan +13 more
core
Intermediate syndrome in organophosphate poisoning: case series [PDF]
, 2017 Acute organophosphate insecticide poisoning is very common in developing countries and the mortality is high because of lack of adequate hospitalization, inadequate atropinization and undiagnosed intermediate syndrome which occur within 24-96 hour after ...
Ochieng, I.A., Saini, P.C.
core +2 more sources
Pharmacological applications of azomethine derivatives in the therapy of different diseases [PDF]
PharmaciaCompounds with an azomethine structure belong to different chemical classes—they are hydrazones, phenylhydrazones, semicarbazones, thiosemicarbazones, and oximes.
Ivanka Pencheva +2 more
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The Mechanism by Which Oximes Reactivate Cholinesterases Inhibited by Organophosphates [PDF]
, 2013 The enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are inhibited by nerve agents such as sarin and tabun. In general, the inhibited enzymes are reactivated by bisquaternary ammonium compounds (oximes).
Bhavaraju, Manikanthan Hari Naga Venkata
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Acetylcholine content in the brain of rats treated with paraoxon and obidoxime [PDF]
British Journal of Pharmacology, 1970 Summary The effect of obidoxime on the rise in brain acetylcholine caused by the anticholinesterase paraoxon was studied in the rat. In animals poisoned with a sublethal dose of paraoxon and thereafter treated with obidoxime the levels of both “free” and total brain acetylcholine were practically the same as those in rats injected with paraoxon only ...
openaire +2 more sources
Acta Medica, 2010 The studies dealing with mechanism of organophosphates (OP)/nerve agent action, prophylaxis and treatment of intoxications is a very hot topic at present.
Jiří Bajgar
doaj +1 more source
Case Report of Acute Kidney Injury in Organophosphorus Poisoning and Potential Association with Oxime Use [PDF]
Asia Pacific Journal of Medical ToxicologyIntroduction: Organophosphorus poisoning (OP) represents a significant public health issue, particularly in developing countries, due to its extensive availability and high toxicity.
Nourhan Saeed +2 more
doaj +1 more source
Experimental Oximes as Organophosphate Preexposure Prophylaxis. Lessons from the Gulf War Syndrome [PDF]
The present study was undertaken in order to determine if established or experimental K-oximes can protect from OP (paraoxon) toxicity. Rats that received only the OP were compared with those that had received oxime pretreatment before OP exposure.
Kuca, Kamil +2 more
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Acetilkolinesteraza u eritrocitima i butirilkolinesteraza u plazmi - Važni pokazatelji za liječenje osoba otrovanih organofosfornim spojevima [PDF]
, 2007 Inhibition of acetylcholinesterase (AChE) is regarded as the primary toxic mechanism of organophosphorus compounds (OP). Therapeutic strategies are directed to antagonise overstimulation of muscarinic receptors with atropine and to reactivate inhibited ...
A Smith +53 more
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