Odnos strukture i aktivnosti u reaktivaciji tabunom fosforilirane ljudske acetilkolinesteraze bispiridinijevim para-aldoksimima [PDF]
, 2007 We investigated interactions of bispyridinium para-aldoximes N,N’-(propano)bis(4-hydroxyiminomethyl) pyridinium bromide (TMB-4), N,N’-(ethano)bis(4-hydroxyiminomethyl)pyridinium methanosulphonate (DMB-4), and N,N’-(methano)bis(4-hydroxyiminomethyl ...
A Bosak +28 more
core +2 more sources
Uticaj natrijum bikarbonata i standardnih antidota na acido-bazni status pacova trovanih dihlorvosom [PDF]
, 2004 The aim of the present work was to examine potential beneficial role of sodium bicarbonate (3 mmol/kg ip) on protective potency of trimedoxime (10 mg/kg im), obidoxime (10 mg/kg im) and atropine (10 mg/kg im) in rats poisoned with dichlorvos.
Antonijević, Biljana +5 more
core +1 more source
Novi uvidi u intermedijarni sindrom uzrokovan trovanjem organofosfatnim pesticidom [PDF]
, 2018 Acute organophosphate (OP) poisoning can be deadlier than any other type of chemical poisoning. So far, only a few cases have been described that include extensive neurological complications.
Bianca Codrina Morarasu +4 more
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Advances in toxicology and medical treatment of chemical warfare nerve agents [PDF]
, 2012 Organophosphorous (OP) Nerve agents (NAs) are known as the deadliest chemical warfare agents. They are divided into two classes of G and V agents. Most of them are liquid at room temperature.
Emadodin Darchini-Maragheh +2 more
core +1 more source
Zaštitni efekat kombinacije HI-6 i trimedoksima u miševa akutno trovanih tabunom, dihlorvosom ili heptenofosom [PDF]
, 2012 The aim of this study was to compare the protective effect of two individual oximes (HI-6 and trimedoxime) with their combination in mice acutely poisoned with tabun, dichlorvos or heptenophos.
Antonijević, Biljana +2 more
core +3 more sources
Treatment efficacy in a soman-poisoned guinea pig model: added value of physostigmine? [PDF]
, 2010 Current treatment of organophosphate poisoning is insufficient, and survivors may suffer from long-lasting adverse effects, such as cognitive deficits and sleep-wake disturbances.
August B. Smit +2 more
core +4 more sources
Terapijska i neuroprotektivna djelotvornost profilakse i primjene protuotrova u liječenju akutnog otrovanja tabunom odnosno somanom s posebnim osvrtom na profilaksu PANPAL-om [PDF]
, 2006 A good knowledge of the basic mechanisms of acute toxicity of organophosphorus compounds has lead to the development of specific antidotes able to counteract their acute toxic effects.
Jiři Kassa
core +1 more source
Characterization of cholinesterase activities for pesticide exposure in food animals [PDF]
, 2012 The primary aim of the work described in this thesis is to establish a foundation for the applicability of a biochemical biomarker, cholinesterase (ChE) activity in food animal species, as an instrument for evaluating exposure to pollutants as well as ...
Abass Askar, Kasim Sakran
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Improving poisoning management through (A) A pilot study to evaluate the use of the triple cholinesterase test in Organophosphorus poisoning and (B) A study on the changing profile of poisoning presenting to a tertiary care centre in South India [PDF]
, 2016 OBJECTIVES: 1. To validate the triple cholinesterase test for use in patients with organophosphorus poisoning – RBC acetylcholinesterase (AChE), Plasma butyrylcholinesterase (BChE), enzyme reactivating potential of obidoxime ex-vivo and Inhibitory ...
Sandhya, Suresh
core
Supstituirani monokvaterni oksimi kao reaktivatori acetilkolinesteraze inhibirane ciklosarinom i klorpirifosom [PDF]
, 2006 This paper describes an in vitro study of three potential acetylcholinesterase (AChE; EC 3.1.1.7) reactivators derived from a monoquaternary reactivator pralidoxime.
Daniel Jun +3 more
core +1 more source