Review of Possible Therapies in Treatment of Novichoks Poisoning and HAZMAT/CBRNE Approaches: State of the Art. [PDF]
J Clin Med, 2023 Noga M, Michalska A, Jurowski K.
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Efficacy of atropine sulfate/obidoxime chloride co-formulation against sarin exposure in guinea pigs
, 2018 The efficacy and pharmacokinetics of the aqueous co-formulation contents of the Trobigard™ (atropine sulfate, obidoxime chloride) auto-injector were evaluated in a sarin exposed guinea pig model. Two subcutaneous (sc) sarin challenge doses were evaluated
Groningen, T. van +7 more
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Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice. [PDF]
Toxics, 2022 Kassa J +4 more
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, 1994 The oximes HI-6, HLo-7, HGG-12, HGG-42 and obidoxime were used in a previously developed rat model to evaluate the therapeutic effects of oximes other than acetylcholinesterase (AChE) reactivation (so-called 'nonreactivating effects').
Wiel, H.J. van der +4 more
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In Vitro Evaluation of Oxidative Stress Induced by Oxime Reactivators of Acetylcholinesterase in HepG2 Cells. [PDF]
Chem Res Toxicol, 2023 Váňová N +5 more
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Experimental and Established Oximes as Pretreatment before Acute Exposure to Azinphos-Methyl. [PDF]
Int J Mol Sci, 2021 Lorke DE +4 more
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Editorial: Case reports in predictive toxicology: 2022. [PDF]
Front Pharmacol, 2023 Fröhlich E, Steinritz D.
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A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning. [PDF]
J Med Chem, 2022 Da Silva O +16 more
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Assessment of four organophosphorus pesticides as inhibitors of human acetylcholinesterase and butyrylcholinesterase. [PDF]
Sci Rep, 2021 Čadež T +3 more
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