Results 101 to 110 of about 706 (177)

Treatment efficacy in a soman-poisoned guinea pig model: Added value of physostigmine?

, 2011
Current treatment of organophosphate poisoning is insufficient, and survivors may suffer from long-lasting adverse effects, such as cognitive deficits and sleep-wake disturbances.
Joosen, M.J.A., Smit, A.B., Helden, H.P.M. van   +2 more
core  

Screening of efficient salicylaldoxime reactivators for DFP and paraoxon-inhibited acetylcholinesterase. [PDF]

RSC Med Chem
Wei Z, Zhang D, Liu X, Nie H, Ouyang Q, Zhang X, Zheng Z.   +6 more
europepmc   +1 more source

From Mechanisms to Materials: Oximate Reactivity and Emerging Strategies for Organophosphate Detoxification. [PDF]

Chemphyschem
Rodríguez-Dafonte P.
europepmc   +1 more source

Pharmacokinetics of three novel pyridinium aldoxime acetylcholinesterase reactivators in female rats. [PDF]

Toxicol Appl Pharmacol, 2022
Backer BS, Meek EC, Ross MK, Chambers JE.   +3 more
europepmc   +1 more source

A-series agent A-234: initial in vitro and in vivo characterization. [PDF]

Arch Toxicol
Hrabinova M, Pejchal J, Hepnarova V, Muckova L, Junova L, Opravil J, Zdarova Karasova J, Rozsypal T, Dlabkova A, Rehulkova H, Kucera T, Vecera Z, Caisberger F, Schmidt M, Soukup O, Jun D.   +15 more
europepmc   +1 more source

An HBT-based "off-on" fluorescent probe for direct detection of methyl parathion in environmental water and Chinese medicine samples. [PDF]

RSC Adv
Geng Y, Zhang W, Li LT, Tian Y, Zhai BQ, Bi WZ, Wang YG.   +6 more
europepmc   +1 more source

Synthesis and preliminary biological evaluation of gabactyzine, a benactyzine-GABA mutual prodrug, as an organophosphate antidote. [PDF]

Sci Rep, 2022
Weitman M, Eisenkraft A, TaShma Z, Makarovsky I, Last D, Daniels D, Guez D, Shneor R, Mardor Y, Nudelman A, Krivoy A.   +10 more
europepmc   +1 more source

Albuterol as an adjuvant in acute anticholinesterase pesticide poisoning: a randomized, placebo-controlled clinical trial. [PDF]

Toxicol Res (Camb)
Zein-Elabdeen SMM, Hassan NA, El-Ebiary AA, Hafez ASAF, Hodeib AA.   +4 more
europepmc   +1 more source

Organophosphorus compounds and oximes: a critical review. [PDF]

Arch Toxicol, 2020
Worek F, Thiermann H, Wille T.
europepmc   +1 more source

A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making. [PDF]

Arch Toxicol, 2020
Amend N, Langgartner J, Siegert M, Kranawetvogl T, Koller M, John H, Pflügler C, Mögele-Schmid C, Worek F, Thiermann H, Wille T.   +10 more
europepmc   +1 more source