Management of Treatment and Prevention of Acute OP Pesticide Poisoning by Medical Informatics, Telemedicine and Nanomedicine [PDF]
, 2013 Acute organophosphorous pesticide (OP) poisoning kills a lot of people each year. Treatment of acute OP poisoning is of very difficult task and is a time taking event.
Anurag Singh Chauhan +13 more
core
Pharmacological applications of azomethine derivatives in the therapy of different diseases [PDF]
PharmaciaCompounds with an azomethine structure belong to different chemical classes—they are hydrazones, phenylhydrazones, semicarbazones, thiosemicarbazones, and oximes.
Ivanka Pencheva +2 more
doaj +3 more sources
Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]
, 2012 Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke +3 more
core +1 more source
Acta Medica, 2010 The studies dealing with mechanism of organophosphates (OP)/nerve agent action, prophylaxis and treatment of intoxications is a very hot topic at present.
Jiří Bajgar
doaj +1 more source
Acetylcholine content in the brain of rats treated with paraoxon and obidoxime [PDF]
British Journal of Pharmacology, 1970 Summary The effect of obidoxime on the rise in brain acetylcholine caused by the anticholinesterase paraoxon was studied in the rat. In animals poisoned with a sublethal dose of paraoxon and thereafter treated with obidoxime the levels of both “free” and total brain acetylcholine were practically the same as those in rats injected with paraoxon only ...
openaire +2 more sources
In vitro evaluation of neutral oximes as reactivators of parathion-inhibited electric eel acetylcholinesterase [PDF]
, 2017 Organophosphorus (OP) compounds are irreversible inhibitors of acetylcholinesterase (AChE) commonly used as pesticides and, unfortunately, as nerve agents in terrorist attacks.
Aguiar, Alcino P. +5 more
core +2 more sources
Case Report of Acute Kidney Injury in Organophosphorus Poisoning and Potential Association with Oxime Use [PDF]
Asia Pacific Journal of Medical ToxicologyIntroduction: Organophosphorus poisoning (OP) represents a significant public health issue, particularly in developing countries, due to its extensive availability and high toxicity.
Nourhan Saeed +2 more
doaj +1 more source
Experimental Oximes as Organophosphate Preexposure Prophylaxis. Lessons from the Gulf War Syndrome [PDF]
The present study was undertaken in order to determine if established or experimental K-oximes can protect from OP (paraoxon) toxicity. Rats that received only the OP were compared with those that had received oxime pretreatment before OP exposure.
Kuca, Kamil +2 more
core +2 more sources
Effect of sodium bicarbonate in rats acutely poisoned with dichlorvos [PDF]
, 2006 The development of effective antidotes against organophosphates such as dichlorvos has been a persistent challenge over the past decades. Therapy of organophosphate poisoning is based on the administration of atropine and oxime as standard antidotes. The
Antonijević, Biljana +5 more
core +2 more sources
A comparison of the neuroprotective efficacy of newly developed oximes (K117, K127) and currently available oxime (obidoxime) in tabun-poisoned rats [PDF]
The potency of newly developed bispyridinium compounds (K117, K127) to reduce tabun-induced acute neurotoxic signs and symptoms was compared with currently available oxime (obidoxime) using functional observational battery. The neuroprotective effects of
Cabal J. +19 more
core +2 more sources