Nanochanneled Device and Related Methods [PDF]
, 2013 A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device.
Ferrari, Mauro +7 more
core +2 more sources
Journal of Biomedical Science, 1993 The efficacies and mechanisms of obidoxime in antagonizing the neuromuscular failure induced by neostigmine and diisopropyl fluorophosphate (DFP) were studied in mouse phrenic nerve/diaphragm preparations. Obidoxime antagonized neostigmine-induced tetanic fade (EC(50): 300 &mgr;M) by inhibiting the regenerative and sustained depolarization during ...
L.C., Chiou, C.C., Chang
openaire +2 more sources
Acetilkolinesteraza u eritrocitima i butirilkolinesteraza u plazmi - Važni pokazatelji za liječenje osoba otrovanih organofosfornim spojevima [PDF]
, 2007 Inhibition of acetylcholinesterase (AChE) is regarded as the primary toxic mechanism of organophosphorus compounds (OP). Therapeutic strategies are directed to antagonise overstimulation of muscarinic receptors with atropine and to reactivate inhibited ...
A Smith +53 more
core +2 more sources
Odnos strukture i aktivnosti u reaktivaciji tabunom fosforilirane ljudske acetilkolinesteraze bispiridinijevim para-aldoksimima [PDF]
, 2007 We investigated interactions of bispyridinium para-aldoximes N,N’-(propano)bis(4-hydroxyiminomethyl) pyridinium bromide (TMB-4), N,N’-(ethano)bis(4-hydroxyiminomethyl)pyridinium methanosulphonate (DMB-4), and N,N’-(methano)bis(4-hydroxyiminomethyl ...
A Bosak +28 more
core +2 more sources
Novi uvidi u intermedijarni sindrom uzrokovan trovanjem organofosfatnim pesticidom [PDF]
, 2018 Acute organophosphate (OP) poisoning can be deadlier than any other type of chemical poisoning. So far, only a few cases have been described that include extensive neurological complications.
Bianca Codrina Morarasu +4 more
core +2 more sources
Terapijska i neuroprotektivna djelotvornost profilakse i primjene protuotrova u liječenju akutnog otrovanja tabunom odnosno somanom s posebnim osvrtom na profilaksu PANPAL-om [PDF]
, 2006 A good knowledge of the basic mechanisms of acute toxicity of organophosphorus compounds has lead to the development of specific antidotes able to counteract their acute toxic effects.
Jiři Kassa
core +1 more source
Acetylcholinesterase Reactivators Antagonize Epileptiform ~u r a i n g Induced by Paraoxon in ~u i n e a Pig Hippocampal Slices [PDF]
, 2020 The electrophysldoglcal actions of paraoxon, an irreversible blocker of acetylcholinesterase, and their antagonism by a series of organophosphate cholinesterase reactivators, were studied in area CAI of the guinea pig hippocampus in vitro.
&apos +5 more
core
Characterization of cholinesterase activities for pesticide exposure in food animals [PDF]
, 2012 The primary aim of the work described in this thesis is to establish a foundation for the applicability of a biochemical biomarker, cholinesterase (ChE) activity in food animal species, as an instrument for evaluating exposure to pollutants as well as ...
Abass Askar, Kasim Sakran
core +1 more source
Review of Possible Therapies in Treatment of Novichoks Poisoning and HAZMAT/CBRNE Approaches: State of the Art. [PDF]
J Clin Med, 2023 Noga M, Michalska A, Jurowski K.
europepmc +1 more source
Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice. [PDF]
Toxics, 2022 Kassa J +4 more
europepmc +1 more source