Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review). [PDF]
Li S +11 more
europepmc +1 more source
CMTR‐Gel targeting to the inflamed mucosa by electrostatic interactions. ABSTRACT Natural drug‐food homology compounds have vast therapeutic potential, particularly for inflammatory bowel disease (IBD), but their poor water solubility, instability, and limited mucosal availability hinder their clinical translation.
Wenqiu Xu +7 more
wiley +1 more source
The supernatant of <i>Lactiplantibacillus plantarum</i> 25 is more effective than extracellular vesicles in alleviating ulcerative colitis and improving intestinal barrier function. [PDF]
Gong S +5 more
europepmc +1 more source
MOSH‐induced colonic alterations and sex‐specific metabolic pathways in female and male F344 rats. ABSTRACT This study investigated the effects of mineral oil saturated hydrocarbon (MOSH) sub‐fractions (C20‐30 and C30‐50) on the colon of male and female F344 rats and the underlying mechanisms.
Lin Zhu +6 more
wiley +1 more source
Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model. [PDF]
Cennet O +5 more
europepmc +1 more source
Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source
High-altitude hypoxia exacerbates gastric mucosal damage and regulates the Nrf2 signaling pathway in <i>Helicobacter pylori</i>-infected mice. [PDF]
Li C, Wang X, Cui S.
europepmc +1 more source
ABSTRACT Background With increasing use of intrapartum antibiotic prophylaxis (IAP) for the prevention of early‐onset Group B streptococcus (GBS) infections, there is concern about its long‐term consequences on child health. Objectives To synthesise the evidence of IAP exposure on autoimmune‐related diseases, obesity in childhood and microbial ...
Maedeh Moradi +3 more
wiley +1 more source
Tight junction proteins: Gatekeepers turned facilitators in the pathogenesis of gastric adenocarcinoma. [PDF]
Selvam S, Vairappan B.
europepmc +1 more source
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak +7 more
wiley +1 more source

