Thymosin β4 stabilizes hypoxia induced brain microvascular endothelial cell dysfunction through S1PR1 dependent mechanisms. [PDF]
Stewart WG +3 more
europepmc +1 more source
Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram +6 more
wiley +1 more source
Acupuncture improves blood-brain barrier integrity through multi-targeted mechanisms: a preclinical meta-analysis. [PDF]
Zhang K, Liang Y, Wang Y, Yin T, Ming K.
europepmc +1 more source
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Causal Effect of Dietary Patterns on Cerebral Small Vessel Disease: A Mendelian Randomization Study
This Mendelian randomization (MR) study reveals causal links between dietary factors and cerebral small vessel disease (CSVD) neuroimaging markers. Genetically predicted higher polyunsaturated fatty acid (PUFA) levels reduce white matter hyperintensity volume, while monounsaturated fatty acid (MUFA) intake lowers lobar brain microbleeds (BMB) risk.
Yong Zeng +5 more
wiley +1 more source
PotD contributes to Streptococcus suis-induced blood-brain barrier disruption by regulating arcA transcription. [PDF]
Lang S +8 more
europepmc +1 more source
Polysaccharides play a pivotal role in the development of safe and healthy foods. They ameliorate fatigue, preserve the microflora of the gastrointestinal tract, and provide health for the gut in living organisms. These biopolymers are applied for the fabrication of breakthrough drug delivery systems and potential platforms in regenerative medicine ...
M V N L Chaitanya +14 more
wiley +1 more source
Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis. [PDF]
Xia C +5 more
europepmc +1 more source
Nexus of Whey Proteins, Gut Dysbiosis, and Colonic Health
Whey proteins possess antimicrobial and prebiotic properties that modulate gut microbiota by promoting beneficial bacteria like Bifidobacterium while suppressing pathogens. This modulation enhances short‐chain fatty acid production and strengthens intestinal barrier integrity, potentially alleviating dysbiosis‐related conditions such as colitis and ...
Tolulope Joshua Ashaolu +4 more
wiley +1 more source
Activated notch signaling pathway protects the intestinal barrier in DSS-induced colitis by regulating tight junctions. [PDF]
Li T +5 more
europepmc +1 more source

