Results 131 to 140 of about 6,916 (201)

Expression and function of CYP enzymes and hepatobiliary transporters in an improved long-term sandwich culture hepatocyte model. [PDF]

Sci Rep
Pacsuta J, Bárány N, Kiszelák K, Csíkvári O, Mártonné Tóth B, Jemnitz K, Gáborik Z.   +6 more
europepmc   +1 more source

Accurate variant effect estimation in FACS-based deep mutational scanning data with Lilace. [PDF]

Genome Biol
Freudenberg J, Rao J, Howard MK, Macdonald C, Greenwald NF, Coyote-Maestas W, Pimentel H.   +6 more
europepmc   +1 more source

New Machine Learning Models for Predicting the Organic Cation Transporters OCT1, OCT2, and OCT3 Uptake. [PDF]

ACS Omega
Bocci G, Mathai N, Suutari B, Harrison J, Speichert S, Gooyit M, Pires DEV, Overington JP.   +7 more
europepmc   +1 more source

Role of solute carrier transporters in the biodistribution and toxicity of chemotherapeutic drugs. [PDF]

Pharmacol Rev
Boeckman M, Drabison T, Germakovski A, Warmuth A, Ahmed B, Chowdhury AT, Hu S, Sprowl JA, Sparreboom A, Huang KM.   +9 more
europepmc   +1 more source

Target Class Repurposing Across Membrane Transporter Families Provides Privileged Ligands to Address Specific and Undruggable Pharmacological Targets. [PDF]

ACS Pharmacol Transl Sci
Rafehi M, Tägl F, Arlt NS, Neif M, Stefan K, Ismail Al-Khalil W, Busch H, Möller M, König J, Namasivayam V, Stefan SM.   +10 more
europepmc   +1 more source

Ecotoxicity of Nitrated Monoaromatic Hydrocarbons in Aquatic Systems: Emerging Risks from Atmospheric Deposition of Biomass Burning and Anthropogenic Aerosols. [PDF]

Toxics
Bakija Alempijević S, Strmečki S, Mihaljević I, Frka S, Dragojević J, Jakovljević I, Smital T.   +6 more
europepmc   +1 more source

Identification of high-risk SNPs in SLC22A transporter genes: their potential role in PCOS and metformin uptake. [PDF]

BMC Genom Data
Harini R, Usha B, Satish R, Akshatha P, Vijaya Kumar TM.   +4 more
europepmc   +1 more source

Metformin-Associated Gastrointestinal Intolerance: A Narrative Review of Mechanisms and Clinical Management. [PDF]

Clin Med Insights Endocrinol Diabetes
Chen S, Xu B, Lu M.
europepmc   +1 more source

Metformin beyond Glycemic Control: New Mechanistic Insights and Expanding Therapeutic Horizons. [PDF]

Diabetes Metab J
Han E, Nam JH, Lee I, Ku CR, Lee YH.
europepmc   +1 more source

Back to the Future: Repurposing Metformin, a Metabolically Active Drug, to Treat Mild-to-Moderate Ulcerative Colitis. [PDF]

Metabolites
Antonelli E, Dell'Era A, Maconi G, Bassotti G.   +3 more
europepmc   +1 more source