Results 121 to 130 of about 6,916 (201)

The divergent roles of tryptophans W354 and W217 in OCT1 transport: Similar localization, distinct functions. [PDF]

J Biol Chem
Römer S, Ebel L, Neumann A, Rönnpagel V, Schulig L, Meyer-Tönnies MJ, Tzvetkov MV.   +6 more
europepmc   +1 more source

Pharmacogenomic insights into OCT1, OCT3 Variants Affecting Metformin Efficacy in Type 2 Diabetes: A Systematic Review and Meta-Analysis

Endocrinology Research and Practice
Type 2 diabetes mellitus (T2DM) poses a significant global health burden, particularly in India. Metformin is the first-line therapy for T2DM; however, substantial interindividual variability in glycemic response remains a clinical challenge.
Varsha Iranna Dalal
doaj  

Identification of Brimonidine as a Novel Substrate of Organic Cation Transporters OCT2 and MATE1 Expressed in Human Eye. [PDF]

Invest Ophthalmol Vis Sci
Kölz C, Neul C, Hofmann U, Dressler JC, Süsskind D, Wissinger B, Schwab M, Nies AT.   +7 more
europepmc   +1 more source

Ternary complexes in protein-DNA interactions: Kinetics and mechanisms. [PDF]

J Biol Chem
Hefetz A, Rogoulenko E, Levy Y.
europepmc   +1 more source

Prediction model for metformin intolerance in Chinese elderly patients with type 2 diabetes: derivation and external validation in a cross‑sectional study. [PDF]

BMC Endocr Disord
Tan W, Li Y, Lu B, Zhang J, Huang Y.
europepmc   +1 more source

The organic cation transporters 1 and 2 mediate ethanolamine cellular efflux and control systemic phosphatidylethanolamine level. [PDF]

J Biol Chem
Schubert J, Koca F, Barone F, Corona G, Ciarimboli G, Visentin M.   +5 more
europepmc   +1 more source

<i>Ex vivo</i> perfusion model of mouse liver and its application to analyze the effects of OCT1 deficiency. [PDF]

Front Pharmacol
Rönnpagel V, Morof F, Ciarimboli G, Grube M, Meyer-Tönnies MJ, Tzvetkov MV.   +5 more
europepmc   +1 more source

Intracellular Pharmacokinetics of Antidiabetic Drugs: A Focused Narrative Review of Subcellular Distribution (2015-2025). [PDF]

Diseases
Bafail DA.
europepmc   +1 more source

Biphasic dysglycemia induced by pentamidine and detected by intermittently scanned continuous glucose monitoring: a case report of a possible drug-drug interaction with clopidogrel and literature review. [PDF]

J Pharm Health Care Sci
Nakano Y, Kuhara N, Sogawa R, Yasukochi H, Okayama Y, Motoya M, Ishii H, Hasuwa H, Shimanoe C.   +8 more
europepmc   +1 more source

Health risks of cocaine adulteration: local anesthetics as modulators of monoamine and organic cation transporters. [PDF]

Front Pharmacol
Kudlacek O, Senning N, Karden A, Ludwig I, Bicher J, Kooti F, Holy M, Stockner T, Luf A, Sitte HH.   +9 more
europepmc   +1 more source