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Biopharmaceutics and Drug DispositionOriginal data-E1: metabolomics; E2: differentially Metabolites; E3: uptake of metabolites in control/OCT2-overexpressing cells; E4: uptake of metabolites in control/MATE1-overexpressing cells; E5: validation of potential biomarkers in vitro; E6 ...
Yanrong Ma, Xinan Wu, Xin’An Wu
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OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine
Pharmacogenetics and Genomics, 2008Genetic polymorphisms of organic cation transporter 2 (OCT2) have been recently described, but their genotype-phenotype relationship in humans is unknown. We performed this study to (i) characterize genetic variations of the OCT2 gene in the Chinese population and (ii) investigate the potential functional significance of OCT2 polymorphisms using ...
Zhi-Jun, Wang +3 more
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[Expression of Oct2 and its significance in lymphoma diagnosis].
Zhonghua bing li xue za zhi = Chinese journal of pathology, 2007To investigate the specificity and sensitivity of Oct2 protein expression in lymphoma cells and its significance in diagnosis and classification of lymphoma.Formalin-fixed and paraffin-embedded materials from 129 cases of lymphoma and 10 cases of reactive lymphoid hyperplasia (RLH) were studied by EnVision immunohistochemistry for Oct2 protein.Oct2 was
Xiang-rong, Zhao, Da-lie, Ma
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Fampridine is a substrate and inhibitor of human OCT2, but not MATE1 and MATE2K
Drug Metabolism and Pharmacokinetics, 2018Christopher Rowbottom +4 more
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