Results 51 to 60 of about 147,099 (176)

Trans differentiating human adipose-derived mesenchymal stem cells into male germ-like cells utilizing Rabbit Sertoli cells: An experimental study

open access: yesInternational Journal of Reproductive BioMedicine, 2022
Background: Mesenchymal stem cells (MSCs) are deemed as potential new therapeutic agents for infertility treatment and adipose tissue (AT) becomes a potential MSCs source.
Alaa Mutee' Khudair   +2 more
doaj   +1 more source

Secretopathies emerge as a new class of neurocristopathies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira   +3 more
wiley   +1 more source

Ghrelin gene single nucleotide polymorphisms and their effects on Nile tilapia (Oreochromis niloticus) growth

open access: yesAquaculture Reports, 2020
In teleosts, ghrelin plays an important role in body weight gain. This hormone has been used in functional studies on food intake and foraging-related behaviors. However, the regulatory role of its 5′ flanking and coding regions is unknown.
Binglin Chen   +6 more
doaj   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto   +21 more
wiley   +1 more source

Endosialin-expressing bone sarcoma stem-like cells are highly tumor-initiating and invasive

open access: yesMolecular Medicine Reports, 2015
It has been reported that the presence of a small group of cancer stem-like 'side population (SP)' cells is responsible for therapy failure and tumor recurrence.
Dong-xiu Sun   +3 more
semanticscholar   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

open access: yesInterdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen   +6 more
wiley   +1 more source

True hermaphroditism with dysgerminoma

open access: yesMedicine, 2020
Introduction: True hermaphroditism is a rare and usually sporadic disorder. It is defined by the presence of both ovarian and testicular tissues together as ovotestis.
Chun-Qiao Chen   +4 more
semanticscholar   +1 more source

PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang   +5 more
wiley   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho   +7 more
wiley   +1 more source

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