A Comprehensive Review on Dry Eye Disease: Diagnosis, Medical Management, Recent Developments, and Future Challenges [PDF]
, 2015 Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) is a common disorder of the tear film caused by decreased tear production or increased evaporation and manifests with a wide variety of signs and symptoms.
Askarkar, S +4 more
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International Journal of Advanced Research in Science, Communication and Technology, 2023 The projected advent of new medications with short biological half-lives, whose efficacy may depend on a more continuous drug supply than eyedrops can offer, is one reason why innovative ocular drug delivery methods are currently garnering more consideration. moreover due to the possibility for various delivery methods to lessen the negative effects of
null Nikita Jadhav +2 more
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Drug Delivery, 2023 Recently, various novel drug delivery systems have been developed to overcome ocular barriers in order to improve drug efficacy. We have previously reported that montmorillonite (MT) microspheres (MPs) and solid lipid nanoparticles (SLNs) loaded with the
Huamei Li +12 more
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Improving Melatonin Delivery Within the Eye [PDF]
, 2017 Melatonin is a neurohormone synthesized in the pineal gland as well as in other organs and it plays an important role in many ocular functions, as it is synthesized in numerous eye structures.
Alkozi, Hanan Awad, Pintor, Jesús
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Revolutionizing ocular drug delivery: recent advancements in in situ gel technology
Bulletin of the National Research Centre, 2023 Background Ophthalmic in situ gel is a novel preparation. It can be instilled into the eye as a liquid but gels upon contact with the ocular surface, generating a sustained-release depot of the drug.
Susanta Paul +2 more
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A Review on Ocular Novel Drug Delivery Systems of Antifungal Drugs: Functional Evaluation and Comparison of Conventional and Novel Dosage Forms [PDF]
Advanced Pharmaceutical Bulletin, 2021 Ocular fungal infections affect more than one million people annually worldwide. They can lead to impaired vision or even complete blindness, so they should be treated immediately to prevent such consequences.
Saba Mehrandish, Shahla Mirzaeei
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In Vitro Cell Models for Ophthalmic Drug Development Applications [PDF]
, 2016 © Sara Shafaie et al. 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
Ahmed I +46 more
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Vectorisation intra-oculaire [Drug delivery to target the posterior segment of the eye]. [PDF]
, 2004 Retinal diseases are nowadays the most common causes of vision threatening in developed countries. Therapeutic advances in this field are hindered by the difficulty to deliver drugs to the posterior segment of the eye.
Behar-Cohen, F.
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Therapeutics and carriers: The dual role of proteins in nanoparticles for ocular delivery [PDF]
, 2015 © 2015 Bentham Science Publishers. Blindness and visual impairment affect millions of people worldwide and have a very important impact on patients quality of life.
Nicoli, S +3 more
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Approaches in topical ocular drug delivery and developments in the use of contact lenses as drug-delivery devices [PDF]
, 2017 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies,
Acheampong A +17 more
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