Research progress of in-situ gelling ophthalmic drug delivery system
Asian Journal of Pharmaceutical Sciences, 2019 Blindness and vision impairment are the most devastating global health problems resulting in a substantial economic and social burden. Delivery of drug to particular parts of the anterior or posterior segment has been a major challenge due to various ...
Yumei Wu +9 more
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Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]
, 2019 Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
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Pharmaceutics, 2022 Due to complicated anatomical and physical properties, targeted drug delivery to ocular tissues continues to be a key challenge for formulation scientists.
Shery Jacob +8 more
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Insights to Using Contact Lenses for Drug Delivery [PDF]
, 2013 Phan, C.-M. (2013). Insights to Using Contact Lenses for Drug Delivery. Clinical & Experimental Pharmacology, 04(01). https://doi.org/10.4172/2161-1459.1000145There has been considerable interest in the potential application of contact lenses for ocular ...
Gao, Huayi +5 more
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Caspase-mediated pathways in retinal ganglion cell injury: a novel therapeutic target for glaucoma
Frontiers in Cell and Developmental BiologyGlaucoma is a complex disease of the optic nerve leading to vision loss and blindness, with high worldwide incidence and disproportionate prevalence in older populations.
Nisha Rajakrishna +9 more
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Ocular Drug Delivery Role of Contact Lenses
Delhi Journal of Ophthalmology, 2015 Significant advances have been made in order to optimize drug delivery to ocular tissues. There has been considerable interest in the potential application of contact lenses for ocular drug delivery.
Anubhav Chauhan
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Journal of Nanobiotechnology, 2022 Ocular drug delivery is one of the most challenging endeavors among the various available drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic disease, we have not yet succeeded in achieving a proper drug delivery approach
Mehrdad Afarid +2 more
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Recent Developments of Nanostructures for the Ocular Delivery of Natural Compounds
Frontiers in Chemistry, 2022 Ocular disorders comprising various diseases of the anterior and posterior segments are considered as the main reasons for blindness. Natural products have been identified as potential treatments for ocular diseases due to their anti-oxidative ...
Malihe Sadat Razavi +7 more
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Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy [PDF]
, 2017 The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and ...
Barcelona, Pablo Federico +5 more
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Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level. [PDF]
, 2018 ‘A picture is worth a thousand words’ is an idiom from the English language (‘borrowed’ from on old Chinese proverb) that conveys the notion that a complex idea can be succinctly and fully described by a single image. Never has this expression been truer
Andrén, PE +11 more
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