Results 11 to 20 of about 15,982 (300)

Human plasma fibronectin promotes proliferation and differentiation of odontoblast [PDF]

Journal of Applied Oral Science, 2017
Objective To assess the effect of fibronectin (Fn) and porcine type I collagen (PCOL) on odontoblast-like cells in vitro. Material and Methods Rat odontoblast-like cells (MDPC-23 cells) were inoculated and cultured on Fn-coated or type I collagen-coated ...
Jia Tang, Takashi Saito
openalex   +2 more sources

Twist1 Is Essential for Tooth Morphogenesis and Odontoblast Differentiation [PDF]

Journal of Biological Chemistry, 2015
Twist1 is a basic helix-loop-helix-containing transcription factor that is expressed in the dental mesenchyme during the early stages of tooth development.
Tian Meng, Yanyu Huang, Shuzhen Wang, Hua Zhang, Paul C. Dechow, Xiaofang Wang, Chunlin Qin, Bing Shi, Rena N. D’Souza, Yongbo Lu   +9 more
openalex   +2 more sources

Potassium Currents Activated by Depolarization in Odontoblasts [PDF]

Frontiers in Physiology, 2017
Increased intracellular free Ca2+ concentrations elicit plasma membrane depolarization, which leads to the activation of K+ currents. However, the precise properties of K+ currents activated by depolarization in odontoblasts remain to be elucidated.
Yuki Kojima, Maki Kimura, Asuka Higashikawa, Kyosuke Kono, Masayuki Ando, Masakzu Tazaki, Yoshiyuki Shibukawa   +6 more
doaj   +3 more sources

Odontoblast control of dental pulp inflammation triggered by cariogenic bacteria [PDF]

Frontiers in Physiology, 2013
Jean-Christophe eFarges, Jean-Christophe eFarges, Jean-Christophe eFarges, Brigitte eAlliot-licht, Caroline eBaudouin, Philippe eMsika, Françoise eBleicher, Florence eCarrouel, Florence eCarrouel   +8 more
doaj   +2 more sources

Mitochondrial DNA leakage induces odontoblast inflammation via the cGAS-STING pathway

Cell Communication and Signaling, 2021
Mitochondrial DNA (mtDNA) is a vital driver of inflammation when it leaks from damaged mitochondria into the cytosol. mtDNA stress may contribute to cyclic GMP-AMP synthase (cGAS) stimulator of interferon genes (STING) pathway activation in infectious ...
Lu Zhou, Yi-Fei Zhang, Fuhua Yang, Han-Qing Mao, Zhi Chen, Lu Zhang   +5 more
semanticscholar   +1 more source

Odontoblast TRPC5 channels signal cold pain in teeth

Science Advances, 2021
The odontoblast, with processes beyond the dentin-enamel boundary, is the initial site of TRPC5 cold transduction in teeth. Teeth are composed of many tissues, covered by an inflexible and obdurate enamel.
L. Bernal, P. Sotelo-Hitschfeld, Christine König, Viktor Sinica, A. Wyatt, Z. Winter, A. Hein, F. Touška, S. Reinhardt, Aaron Tragl, R. Kusuda, Philipp Wartenberg, A. Sclaroff, J. Pfeifer, F. Ectors, A. Dahl, M. Freichel, V. Vlachova, S. Brauchi, C. Roza, U. Boehm, D. Clapham, J. Lennerz, K. Zimmermann   +23 more
semanticscholar   +1 more source

Gαs-Coupled CGRP Receptor Signaling Axis from the Trigeminal Ganglion Neuron to Odontoblast Negatively Regulates Dentin Mineralization

Biomolecules, 2022
An inflammatory response following dental pulp injury and/or infection often leads to neurogenic inflammation via the axon reflex. However, the detailed mechanism underlying the occurrence of the axon reflex in the dental pulp remains unclear.
Natsuki Saito, M. Kimura, T. Ouchi, T. Ichinohe, Y. Shibukawa   +4 more
semanticscholar   +1 more source

Atp6i deficient mouse model uncovers transforming growth factor-β1 /Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation

International Journal of Oral Science, 2023
The biomolecular mechanisms that regulate tooth root development and odontoblast differentiation are poorly understood. We found that Atp6i deficient mice (Atp6i −/− ) arrested tooth root formation, indicated by truncated Hertwig’s epithelial root sheath
Jue Wang, Abigail McVicar, Yilin Chen, Hong-Wen Deng, Zhihe Zhao, Wei Chen, Yi-Ping Li   +6 more
doaj   +1 more source

Role of connexin 43 in odontoblastic differentiation and structural maintenance in pulp damage repair

International Journal of Oral Science, 2021
Dental pulp can initiate its damage repair after an injury of the pulp–dentin complex by rearrangement of odontoblasts and formation of newly differentiated odontoblast-like cells.
Jiaxin Yin, Jue Xu, Ran Cheng, Meiying Shao, Yuandong Qin, Hui Yang, Tao Hu   +6 more
doaj   +1 more source

Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton. [PDF]

Int Endod J
Abstract Aim This study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic differentiation induced by DCEFs stimulation.
Li X, Zhao S, Liu Y, Gu Y, Qiu L, Chen X, Sloan AJ, Song B.   +7 more
europepmc   +2 more sources