Biomedicines, 2021 Odontoblasts produce proteins that form the dentinal extracellular matrix, which can protect the dental pulp from external stimuli and is required for tooth regeneration.
Han-Moi Lim +3 more
doaj +1 more source
CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts
Frontiers in Cell and Developmental Biology, 2021 Dentin, which composes most of the tooth structure, is formed by odontoblasts, long-lived post-mitotic cells maintained throughout the entire life of the tooth. In mature odontoblasts, however, cellular activity is significantly weakened.
Yeoung-Hyun Park +7 more
doaj +1 more source
Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration
Frontiers in Bioengineering and Biotechnology, 2021 Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which ...
Jiahui Fu +8 more
doaj +1 more source
Presence of matrix vesicles in the body of odontoblasts and in the inner third of dentinal tissue: A scanning electron microscopyc study [PDF]
, 2013 Objectives: The aim of this report is to present the results of a scanning electron microscopic study on the presence of matrix vesicles (MVs) found in human dentine.
Maricela Garcés-Ortı́z +2 more
openalex +2 more sources
Effect of angiopoietin 4 on odontogenic differentiation of dental pulp stem cells
口腔疾病防治, 2023 Objective To investigate the effects of angiopoietin 4 (ANGPT4) on the odontogenic differentiation of human dental pulp stem cells. Methods This study has been reviewed and approved by the Ethics Committee, and informed consent has been obtained from ...
FAN Xinyi +5 more
doaj +1 more source
Immunomodulation stimulates the innervation of engineered tooth organ [PDF]
, 2014 The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault +5 more
core +9 more sources
Matrix metalloproteinase-3 in odontoblastic cells derived from ips cells: unique proliferation response as odontoblastic cells derived from ES cells. [PDF]
PLoS ONE, 2013 We previously reported that matrix metalloproteinase (MMP)-3 accelerates wound healing following dental pulp injury. In addition, we reported that a proinflammatory cytokine mixture (tumor necrosis factor-α, interleukin (IL)-1β and interferon-γ) induced ...
Taiki Hiyama +7 more
doaj +1 more source
International Journal of Molecular Sciences, 2020 The role of dental pulp stem cells (DPSCs) in dental tissue regeneration is gaining attention because DPSCs can differentiate into odontoblasts and other specialized cell types.
Eun-Cheol Lee +4 more
semanticscholar +1 more source
Lack of Fluid Movement between Dentin Tubule and Pulp Tissue: An In Vitro Study
Dental Hypotheses, 2022 Objective: In vitro studies supporting the hydrodynamic theory have reported that cavity provocation results in fluid flow from dentin tubules via pulp tissue to a capillary connected apically. Our preliminary findings did not corroborate this. Therefore,
Chia-Yi Chen, Gunnar Hasselgren
doaj +1 more source
Isolation and Differentiation of Adipose-Derived Stem Cells into Odontoblast-Like Cells: A Preliminary In Vitro Study [PDF]
Cell Journal, 2021 Objective: The aim of present study was to isolate and differentiate human adipose-derived stem cells (ASCs) into odontoblast-like cells. Materials and Methods: In this experimental study, human adipose tissues were taken from the buccal fat pad of ...
Saber Khazaei +5 more
doaj +1 more source