Results 21 to 30 of about 11,439 (266)

Effect of angiopoietin 4 on odontogenic differentiation of dental pulp stem cells

open access: yes口腔疾病防治, 2023
Objective To investigate the effects of angiopoietin 4 (ANGPT4) on the odontogenic differentiation of human dental pulp stem cells. Methods This study has been reviewed and approved by the Ethics Committee, and informed consent has been obtained from ...
FAN Xinyi   +5 more
doaj   +1 more source

Tooth-bone attachment tissue is produced by cells with a mixture of odontoblastic and osteoblastic features in reptiles. [PDF]

open access: yesJ Anat
Tooth attachment in vertebrates ranges from ligament‐based anchorage in mammals to direct fusion in many reptiles. In the veiled chameleon, we identified a transient cell population—termed ankyloblasts—at the tooth‐bone interface. These cells exhibit both odontoblast‐ and osteoblast‐like features.
Šulcová M   +11 more
europepmc   +2 more sources

Matrix metalloproteinase-3 in odontoblastic cells derived from ips cells: unique proliferation response as odontoblastic cells derived from ES cells. [PDF]

open access: yesPLoS ONE, 2013
We previously reported that matrix metalloproteinase (MMP)-3 accelerates wound healing following dental pulp injury. In addition, we reported that a proinflammatory cytokine mixture (tumor necrosis factor-α, interleukin (IL)-1β and interferon-γ) induced ...
Taiki Hiyama   +7 more
doaj   +1 more source

Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which ...
Jiahui Fu   +8 more
doaj   +1 more source

CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts

open access: yesFrontiers in Cell and Developmental Biology, 2021
Dentin, which composes most of the tooth structure, is formed by odontoblasts, long-lived post-mitotic cells maintained throughout the entire life of the tooth. In mature odontoblasts, however, cellular activity is significantly weakened.
Yeoung-Hyun Park   +7 more
doaj   +1 more source

The Histone Deacetylase Inhibitor (MS-275) Promotes Differentiation of Human Dental Pulp Stem Cells into Odontoblast-Like Cells Independent of the MAPK Signaling System

open access: yesInternational Journal of Molecular Sciences, 2020
The role of dental pulp stem cells (DPSCs) in dental tissue regeneration is gaining attention because DPSCs can differentiate into odontoblasts and other specialized cell types.
Eun-Cheol Lee   +4 more
semanticscholar   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell Differentiation Into Odontoblast-Like Cells and Endothelial Cells: A Potential Cell Source for Dental Pulp Tissue Engineering

open access: yesFrontiers in Physiology, 2020
Objectives Dental pulp regeneration is considered an ideal approach for treating dental pulp disease. Because pulp is composed of various cells, determining the proper seed cells is critical.
Shuang Zhang   +8 more
semanticscholar   +1 more source

An Innovative "Tooth-On-Chip" Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue. [PDF]

open access: yesAdv Healthc Mater
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Cordiale A   +6 more
europepmc   +2 more sources

Lack of Fluid Movement between Dentin Tubule and Pulp Tissue: An In Vitro Study

open access: yesDental Hypotheses, 2022
Objective: In vitro studies supporting the hydrodynamic theory have reported that cavity provocation results in fluid flow from dentin tubules via pulp tissue to a capillary connected apically. Our preliminary findings did not corroborate this. Therefore,
Chia-Yi Chen, Gunnar Hasselgren
doaj   +1 more source

In vitro reparative dentin: a biochemical and morphological study

open access: yesEuropean Journal of Histochemistry, 2013
In this study, starting from human dental pulp cells cultured in vitro, we simulated reparative dentinogenesis using a medium supplemented with different odontogenic inductors.
G. Teti   +6 more
doaj   +1 more source

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