Results 81 to 90 of about 24,674 (246)

Role of the odorant receptor in neuronal connectivity in the olfactory bulb

Swiss Medical Weekly, 2015
Olfaction is a highly sophisticated sensory modality able to detect and discriminate thousands of different odours, even at very low concentration. How such a challenging task is achieved remains to be fully understood.
Nelly Redolfi, Claudia Lodovichi
doaj   +1 more source

Exposure to GABAA Receptor Antagonist Picrotoxin in Pregnant Mice Causes Autism-Like Behaviors and Aberrant Gene Expression in Offspring

Frontiers in Psychiatry, 2022
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by impairments in social interaction and restricted/repetitive behaviors.
Hiroko Kotajima-Murakami, Hiroko Kotajima-Murakami, Hideo Hagihara, Atsushi Sato, Atsushi Sato, Yoko Hagino, Miho Tanaka, Miho Tanaka, Yoshihisa Katoh, Yasumasa Nishito, Yukio Takamatsu, Shigeo Uchino, Shigeo Uchino, Tsuyoshi Miyakawa, Kazutaka Ikeda   +14 more
doaj   +1 more source

Organic neuromorphic electronics powering intelligent sensory and edge computing systems

InfoMat, EarlyView.
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo, Minji Chung, Hyun Woo Song, Seoyoung Kim, Eun Kwang Lee, Joon Hak Oh   +5 more
wiley   +1 more source

Rapid encoding and perception of novel odors in the rat. [PDF]

PLoS Biology, 2008
To gain insight into which parameters of neural activity are important in shaping the perception of odors, we combined a behavioral measure of odor perception with optical imaging of odor representations at the level of receptor neuron input to the rat ...
Daniel W Wesson, Ryan M Carey, Justus V Verhagen, Matt Wachowiak   +3 more
doaj   +1 more source

Can trigeminal sensations impact saltiness perception? A mini‐review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan, Nicoletta Faraone, Matthew B McSweeney   +2 more
wiley   +1 more source

Odor Identification Quantitatively by Odorant Receptor Vectors

, 2022
Abstract Background: Odors are perceived by individuals through sensation, memory, experience, etc., and mainly subjective and qualitative evaluation has been performed until now. On the other hand, since Buck et al. succeeded in cloning the odorant receptor in 1991, researchers have shown interest in olfaction system, and molecular biology ...
Kosei Kawai, Shin Morishita
openaire   +1 more source

Olfactory Bulb Volume and Function Recovery in Eosinophilic Chronic Rhinosinusitis

The Laryngoscope, EarlyView.
This study investigated perioperative changes in olfactory bulb volume (OBV) in patients with eosinophilic chronic rhinosinusitis using high‐resolution 3T MRI. Postoperative increases in OBV were associated with improvements in olfactory identification, suggesting a potential link between olfactory bulb structural plasticity and functional recovery ...
Keisuke Yamamoto, Masaki Abukawa, Tsuyoshi Okuni, Mitsuhiro Nakanishi, Yuki Sakurai, Naoya Yama, Noriko Ogasawara, Ryuta Kamekura, Kenichi Takano   +8 more
wiley   +1 more source

Coding Odorant Concentration through Activation Timing between the Medial and Lateral Olfactory Bulb

Cell Reports, 2012
In mammals, each olfactory bulb (OB) contains a pair of mirror-symmetric glomerular maps organized to reflect odorant receptor identity. The functional implication of maintaining these symmetric medial-lateral maps within each OB remains unclear.
Zhishang Zhou, Leonardo Belluscio
doaj   +1 more source

Molecular basis for odorant receptor tuning: a short C-terminal sequence is necessary and sufficient for selectivity of mosquito Or8 [PDF]

, 2015
A birth-and-death evolutionary model for odorant receptor gene repertoires presumes the creation of repertoires with the capacity for high-level diversity and rapid ligand specificity change.
Hill, Sharon, Ignell, Rickard, Majeed, Shahid   +2 more
core   +1 more source

Engineered odorant receptors illuminate structural principles of odor discrimination

, 2023
AbstractA central challenge in olfaction is understanding how the olfactory system detects and distinguishes odorants with diverse physicochemical properties and molecular configurations. Vertebrate animals perceive odors via G protein-coupled odorant receptors (ORs). In humans, ∼400 ORs enable the sense of smell. The OR family is composed of two major
Claire A. de March, Ning Ma, Christian B. Billesbølle, Jeevan Tewari, Claudia Llinas del Torrent, Wijnand J. C. van der Velden, Ichie Ojiro, Ikumi Takayama, Bryan Faust, Linus Li, Nagarajan Vaidehi, Aashish Manglik, Hiroaki Matsunami   +12 more
openaire   +2 more sources