Results 181 to 190 of about 54,368 (362)

A bio. tools collection of online resources for GPCR research

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors are highly complex signal transduction proteins with many potential biomedical applications. Researchers from different fields work together to improve mechanistic understanding of GPCR function and to transfer that knowledge in order to advance therapeutic options.
Tõnis Laasfeld   +9 more
wiley   +1 more source

Exploring the Activation of the Keap1‐Nrf2‐ARE Pathway by PAHs in Children's Toys

open access: yesContact Dermatitis, EarlyView.
Our study evaluated the skin sensitisation risk of polycyclic aromatic hydrocarbons (PAHs) in toys, revealing that B[k]F, B[b]F and chrysene are highly potent sensitizers. Synergistic effects in PAH mixtures underscore the need to consider combined exposures when assessing environmental risks to children.
Jonas Lauenstein   +6 more
wiley   +1 more source

Differential gene expression toward species of Aristolochia impairing the performance of the Troidini butterfly Battus polydamas

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We studied the response of Battus polydamas (Papilionidae) larvae fed on Aristolochia ringens (containing several diterpenes) and Aristolochia gigantea (containing sesquiterpenes and acyclic monoterpenoids but no diterpenoids or aristolochic acids). We assessed larval performance on fitness components such as survival and differential gene expression ...
Karina L. Silva‐Brandão   +3 more
wiley   +1 more source

Bacterial purine metabolism modulates C. elegans development and stress tolerance via DAF‐16

open access: yesThe FEBS Journal, EarlyView.
To investigate the impact of dietary components on animal growth, an Escherichia coli single‐gene deletion library was screened using the Caenorhabditis elegans growth model. Thirty‐four E. coli mutants were identified to delay worm development. Notably, E.
Min Feng   +3 more
wiley   +1 more source

Non-synaptic inhibition between grouped neurons in an olfactory circuit. [PDF]

open access: yes, 2012
Diverse sensory organs, including mammalian taste buds and insect chemosensory sensilla, show a marked compartmentalization of receptor cells; however, the functional impact of this organization remains unclear.
Carlson, John R   +3 more
core  

Q-learning with temporal memory to navigate turbulence [PDF]

open access: yesarXiv
We consider the problem of olfactory searches in a turbulent environment. We focus on agents that respond solely to odor stimuli, with no access to spatial perception nor prior information about the odor. We ask whether navigation to a target can be learned robustly within a sequential decision making framework.
arxiv  

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