Results 91 to 100 of about 97,181 (355)
Mitochondrial network reorganization and transient expansion during oligodendrocyte generation
Nature CommunicationsOligodendrocyte precursor cells (OPCs) give rise to myelinating oligodendrocytes of the brain. This process persists throughout life and is essential for recovery from neurodegeneration.
Xhoela Bame, Robert A. Hill
doaj +1 more source
Journal of Neuroscience, 2005 Demyelination contributes to loss of function after spinal cord injury, and thus a potential therapeutic strategy involves replacing myelin-forming cells.
H. Keirstead +6 more
semanticscholar +1 more source
3D‐Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury
Advanced Healthcare Materials, EarlyView.3D‐printed organoid scaffolds with microscale channels are developed to enhance spinal cord injury recovery by guiding region‐specific spinal neural progenitor cells. These scaffolds promote axonal growth, cell maturation, and neuronal network formation.
Guebum Han +8 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance TDP-43 is the defining pathological hallmark protein for two overlapping adult-onset neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Jia Wang +6 more
semanticscholar +1 more source
Advanced Materials Interfaces, EarlyView.This study presents the first systematic evaluation of interactions between astrocytes and Ti3C2TX MXene flakes, a 2D nanomaterial with emerging neuroelectronic applications. Using a multimodal approach, including viability assays, morphometric analysis, and calcium imaging, this work demonstrates high biocompatibility and preserved function in ...
Dimitris Boufidis +7 more
wiley +1 more source
Monocarboxylate Transporter 8 Deficiency: Delayed or Permanent Hypomyelination?
Frontiers in Endocrinology, 2020 Monocarboxylate transporter 8 (MCT8) deficiency or the Allan-Herndon-Dudley Syndrome (AHDS) is an X-linked psychomotor disability syndrome with around 320 clinical cases described worldwide.
Pieter Vancamp +2 more
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Myelin-oligodendrocyte glycoprotein antibody-associated disease
Lancet Neurology, 2021 R. Marignier +40 more
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Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo
Nature Neuroscience, 2017 How action potentials regulate myelination by oligodendrocytes is uncertain. We show that neuronal activity raises [Ca2+]i in developing oligodendrocytes in vivo and that myelin sheath elongation is promoted by a high frequency of [Ca2+]i transients and ...
A. Krasnow +4 more
semanticscholar +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Role of adenosine in oligodendrocyte precursor maturation
Frontiers in Cellular Neuroscience, 2015 Differentiation and maturation of oligodendroglial cells are postnatal processes involving specific morphological changes correlated with the expression of stage-specific surface antigens and functional voltage-gated ion channels.
Elisabetta eCoppi +6 more
doaj +1 more source