Results 11 to 20 of about 97,181 (355)

Mechanosensitivity of Human Oligodendrocytes [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2020
Oligodendrocytes produce and repair myelin, which is critical for the integrity and function of the central nervous system (CNS). Oligodendrocyte and oligodendrocyte progenitor cell (OPC) biology is modulated in vitro by mechanical cues within the ...
Daniela Espinosa-Hoyos   +10 more
doaj   +4 more sources

The Pathobiology of the Oligodendrocyte [PDF]

open access: bronzeJournal of Neuropathology and Experimental Neurology, 1997
Samuel K. Ludwin
openalex   +4 more sources

Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination

open access: yeseLife, 2023
In the developing central nervous system, oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes, which form myelin around axons. Oligodendrocytes and myelin are essential for the function of the central nervous system, as evidenced ...
Lin Pan   +7 more
doaj   +1 more source

Oligodendrocyte precursor cells engulf synapses during circuit remodeling in mice

open access: yesNature Neuroscience, 2022
Oligodendrocyte precursor cells (OPCs) give rise to myelinating oligodendrocytes throughout life, but the functions of OPCs are not limited to oligodendrogenesis.
Yohan S S Auguste   +10 more
semanticscholar   +1 more source

Oligodendrocytes in a Nutshell [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2015
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). While the phrase is oft repeated and holds true, the last few years have borne witness to radical change in our understanding of this unique cell type. Once considered static glue, oligodendrocytes are now seen as plastic and adaptive, capable of reacting to a changing CNS.
John-Paul eMichalski   +5 more
openaire   +4 more sources

Oligodendrocytes in Schizophrenia [PDF]

open access: yesSchizophrenia Research and Treatment, 2011
Despite the many neuroimaging studies that suggest gray matter volume reductions in schizophrenia, there is no compelling postmortem evidence to suggest neuronal loss, nor is there a distinctive or specific signature of gray matter abnormalities in schizophrenia.
Vahram Haroutunian   +3 more
openaire   +3 more sources

Centenary of the oligodendrocyte

open access: yesThe Lancet Neurology, 2021
“At the banquet of medicine, [histology] is the guest of honor, who eats little—aloof, mysterious—to whom all listen, yet whom very few understand.”1 For Pío del Río-Hortega (Spain, 1882–Argentina, 1945), histology blended the cold and factual with the dynamic, romantic artistry that brought the subject to light.
James, Owen G   +3 more
openaire   +5 more sources

The immunomodulatory oligodendrocyte [PDF]

open access: yesBrain Research, 2016
Oligodendrocytes, the myelinating glial cells of the central nervous system (CNS), are due to their high specialization and metabolic needs highly vulnerable to various insults. This led to a general view that oligodendrocytes are defenseless victims during brain damage such as occurs in acute and chronic CNS inflammation.
Zeis, Thomas   +2 more
openaire   +4 more sources

Pathogenetic Mechanisms Underlying Spinocerebellar Ataxia Type 3 Are Altered in Primary Oligodendrocyte Culture

open access: yesCells, 2022
Emerging evidence has implicated non-neuronal cells, particularly oligodendrocytes, in the pathophysiology of many neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease and ...
Kristen H. Schuster   +2 more
doaj   +1 more source

Oligodendrocyte Development and Plasticity. [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2016
Oligodendrocyte precursor cells (OPCs) originate in the ventricular zones (VZs) of the brain and spinal cord and migrate throughout the developing central nervous system (CNS) before differentiating into myelinating oligodendrocytes (OLs). It is not known whether OPCs or OLs from different parts of the VZ are functionally distinct.
D. Bergles, W. Richardson
semanticscholar   +4 more sources

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