Results 11 to 20 of about 63,056 (297)
The Pathobiology of the Oligodendrocyte [PDF]
Journal of Neuropathology and Experimental Neurology, 1997 Samuel K. Ludwin
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Oligodendrocytes in a Nutshell [PDF]
Frontiers in Cellular Neuroscience, 2015 Oligodendrocytes are the myelinating cells of the central nervous system (CNS). While the phrase is oft repeated and holds true, the last few years have borne witness to radical change in our understanding of this unique cell type. Once considered static glue, oligodendrocytes are now seen as plastic and adaptive, capable of reacting to a changing CNS.
John-Paul eMichalski +5 more
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Oligodendrocytes in Schizophrenia [PDF]
Schizophrenia Research and Treatment, 2011 Despite the many neuroimaging studies that suggest gray matter volume reductions in schizophrenia, there is no compelling postmortem evidence to suggest neuronal loss, nor is there a distinctive or specific signature of gray matter abnormalities in schizophrenia.
Vahram Haroutunian +3 more
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Centenary of the oligodendrocyte
The Lancet Neurology, 2021 “At the banquet of medicine, [histology] is the guest of honor, who eats little—aloof, mysterious—to whom all listen, yet whom very few understand.”1 For Pío del Río-Hortega (Spain, 1882–Argentina, 1945), histology blended the cold and factual with the dynamic, romantic artistry that brought the subject to light.
James, Owen G +3 more
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The immunomodulatory oligodendrocyte [PDF]
Brain Research, 2016 Oligodendrocytes, the myelinating glial cells of the central nervous system (CNS), are due to their high specialization and metabolic needs highly vulnerable to various insults. This led to a general view that oligodendrocytes are defenseless victims during brain damage such as occurs in acute and chronic CNS inflammation.
Zeis, Thomas +2 more
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Nature Reviews Neuroscience, 2006 Oligodendrocyte precursors first arise in a restricted ventral part of the embryonic spinal cord and migrate laterally and dorsally from there. Later, secondary sources develop in the dorsal cord. Normally, the ventrally-derived precursors compete with and suppress their dorsal counterparts.
William D, Richardson +2 more
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Oligodendrocytes: biology and pathology [PDF]
Acta Neuropathologica, 2009 Oligodendrocytes are the myelinating cells of the central nervous system (CNS). They are the end product of a cell lineage which has to undergo a complex and precisely timed program of proliferation, migration, differentiation, and myelination to finally produce the insulating sheath of axons.
Hans Lassmann, Monika Bradl
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Oligodendrocytes in the aging brain [PDF]
Neuronal Signaling, 2021 Abstract More than half of the human brain volume is made up of white matter: regions where axons are coated in myelin, which primarily functions to increase the conduction speed of axon potentials. White matter volume significantly decreases with age, correlating with cognitive decline.
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Generation of Oligodendrocytes and Oligodendrocyte-Conditioned Medium for Co-Culture Experiments [PDF]
Journal of Visualized Experiments, 2020 In the central nervous system, oligodendrocytes are well-known for their role in axon myelination, that accelerates the propagation of action potentials through saltatory conduction. Moreover, an increasing number of reports suggest that oligodendrocytes interact with neurons beyond myelination, notably through the secretion of soluble factors.
Mazuir, Elisa +5 more
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In vivo conversion of astrocytes into oligodendrocyte lineage cells with transcription factor Sox10; Promise for myelin repair in multiple sclerosis. [PDF]
PLoS ONE, 2018 Recent studies demonstrate that astroglial cells can be directly converted into functional neurons or oligodendrocytes. Here, we report that a single transcription factor Sox10 could reprogram astrocytes into oligodendrocyte-like cells, in vivo.
Akram Mokhtarzadeh Khanghahi +4 more
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