Results 11 to 20 of about 88,065 (299)

Mutation of pescadillo disrupts oligodendrocyte formation in zebrafish.

PLoS ONE, 2012
BackgroundIn vertebrates, the myelin sheath is essential for efficient propagation of action potentials along the axon shaft. Oligodendrocytes are the cells of the central nervous system that create myelin sheaths.
Timothy Simmons, Bruce Appel
doaj   +2 more sources

NF-κB RelA regulates temporal oligodendrocyte differentiation in the postnatal brains [PDF]

Frontiers in Cellular Neuroscience
The NF-κB signaling pathway responds to a diverse range of cytokines and extracellular stresses, regulating immune responses, inflammation, cell proliferation, and cell death.
Kamonrapat Sompub, Norihisa Bizen, Albert S. Baldwin, Albert S. Baldwin, Hirohide Takebayashi, Hirohide Takebayashi, Hirohide Takebayashi   +6 more
doaj   +2 more sources

Mitochondrial network reorganization and transient expansion during oligodendrocyte generation [PDF]

Nature Communications
Oligodendrocyte precursor cells (OPCs) give rise to myelinating oligodendrocytes of the brain. This process persists throughout life and is essential for recovery from neurodegeneration.
Xhoela Bame, Robert A. Hill
doaj   +2 more sources

Synaptic vesicle release regulates pre-myelinating oligodendrocyte-axon interactions in a neuron subtype-specific manner [PDF]

Frontiers in Cellular Neuroscience
Oligodendrocyte-lineage cells are central nervous system (CNS) glia that perform multiple functions including the selective myelination of some but not all axons.
James R. Gronseth, Heather N. Nelson, Taylor L. Johnson, Taryn A. Mallon, Madeline R. Martell, Katrina A. Pfaffenbach, Bailey B. Duxbury, John T. Henke, Anthony J. Treichel, Jacob H. Hines   +9 more
doaj   +2 more sources

Intranasal Administration of Undifferentiated Oligodendrocyte Lineage Cells as a Potential Approach to Deliver Oligodendrocyte Precursor Cells into Brain [PDF]

, 2021
Oligodendrocyte precursor cell (OPC) migration is a mechanism involved in remyelination; these cells migrate from niches in the adult CNS. However, age and disease reduce the pool of OPCs; as a result, the remyelination capacity of the CNS decreases over
Vidorreta Ballesteros, Lucía, Inmaculada Sanclemente-Alamán, Doddy Denise Ojeda-Hernández, Matias Guiu, Jordi A., María Soledad Benito-Martín, Jorge Matías-Guiu, Benito Martín, María Soledad, Ojeda Hernández, Doddy Denise, Sara Pérez-Suarez, Mateos Díaz, Juan Carlos, Selma Calvo, Belen, Montero Escribano, Paloma, Juan Carlos Mateos-Díaz, Mercedes A. Hernández-Sapiéns, Francisco Sancho-Bielsa, Lucía Vidorreta-Ballesteros, Pérez Suárez:, Sara, Ulises Gómez-Pinedo, Edwin E. Reza-Zaldívar, Lidia Moreno-Jiménez, Matías-Guiu Guía, Jorge, Hernández Sapiéns, Mercedes A., Alejandro Canales-Aguirre, Jordi A. Matías-Guiu, Belen Selma-Calvo, Paloma Montero-Escribano, Reza Zaldívar, Edwin E., Moreno Jiménez, Lidia, Gómez Pinedo, Ulises, Sancho Bielsa, Francisco, Sanclemente Alamán, Inmaculada, Canales Aguirre, Alejandro, Mateos-Díaz, Juan Carlos, Gómez-Pinedo, Ulises, Moreno-Jiménez, Lidia, Sanclemente-Alamán, Inmaculada, Benito-Martín, María Soledad, Selma-Calvo, Belen, Matías-Guiu, Jordi A, Pérez-Suarez, Sara, Ojeda-Hernández, Doddy Denise, Montero-Escribano, Paloma, Hernández-Sapiéns, Mercedes A, Canales-Aguirre, Alejandro, Sancho-Bielsa, Francisco, Vidorreta-Ballesteros, Lucía, Matías-Guiu, Jorge, Reza-Zaldívar, Edwin E   +47 more
core   +1 more source

Centenary of the oligodendrocyte

The Lancet Neurology, 2021
“At the banquet of medicine, [histology] is the guest of honor, who eats little—aloof, mysterious—to whom all listen, yet whom very few understand.”1 For Pío del Río-Hortega (Spain, 1882–Argentina, 1945), histology blended the cold and factual with the dynamic, romantic artistry that brought the subject to light.
James, Owen G, Mehta, Arpan R, Behari, Madhuri, Chandran, Siddharthan   +3 more
openaire   +4 more sources

Oligodendrocytes in a Nutshell [PDF]

Frontiers in Cellular Neuroscience, 2015
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). While the phrase is oft repeated and holds true, the last few years have borne witness to radical change in our understanding of this unique cell type. Once considered static glue, oligodendrocytes are now seen as plastic and adaptive, capable of reacting to a changing CNS.
John-Paul eMichalski, John-Paul eMichalski, Rashmi eKothary, Rashmi eKothary, Rashmi eKothary, Rashmi eKothary   +5 more
openaire   +3 more sources

The immunomodulatory oligodendrocyte [PDF]

Brain Research, 2016
Oligodendrocytes, the myelinating glial cells of the central nervous system (CNS), are due to their high specialization and metabolic needs highly vulnerable to various insults. This led to a general view that oligodendrocytes are defenseless victims during brain damage such as occurs in acute and chronic CNS inflammation.
Zeis, Thomas, Enz, Lukas, Schaeren-Wiemers, Nicole   +2 more
openaire   +4 more sources

Oligodendrocyte wars [PDF]

Nature Reviews Neuroscience, 2006
Oligodendrocyte precursors first arise in a restricted ventral part of the embryonic spinal cord and migrate laterally and dorsally from there. Later, secondary sources develop in the dorsal cord. Normally, the ventrally-derived precursors compete with and suppress their dorsal counterparts.
William D, Richardson, Nicoletta, Kessaris, Nigel, Pringle   +2 more
openaire   +2 more sources

Oligodendrocytes in Schizophrenia [PDF]

Schizophrenia Research and Treatment, 2011
Despite the many neuroimaging studies that suggest gray matter volume reductions in schizophrenia, there is no compelling postmortem evidence to suggest neuronal loss, nor is there a distinctive or specific signature of gray matter abnormalities in schizophrenia.
Xu, Haiyun, Haroutunian, Vahram, Bartzokis, George, Shenton, Martha E.   +3 more
openaire   +2 more sources