Results 211 to 220 of about 63,056 (297)

Complement dysregulation in human tauopathies

open access: yesBrain Pathology, EarlyView.
Complement protein and activation product levels were assessed in post‐mortem frontal cortex from three distinct subtypes of Tauopathy: Corticobasal degeneration, globular glial tauopathy, and Pick's disease. Quantification of complement proteins by immunohistochemistry and ELISA showed elevation of key complement proteins (C1q) regulators (FI) and ...
Jacqui Nimmo   +3 more
wiley   +1 more source

Multi‐pronged analysis of pediatric low‐grade glioma and ganglioglioma reveals a unique tumor microenvironment associated with BRAF alterations

open access: yesBrain Pathology, EarlyView.
A multi pronged analysis approach revealed distinct neoplastic populations in PA and GG. Non‐neoplastic populations in PA showed higher levels of immune mobilizing chemokines in PA compared to GG. Abstract Pediatric low‐grade gliomas (pLGG) comprise 35% of all brain tumors.
Shadi Zahedi   +19 more
wiley   +1 more source

Intrinsic retinoic acid synthesis is required for oligodendrocyte progenitor expansion during CNS remyelination. [PDF]

open access: yesFront Cell Neurosci
Nanescu SE   +11 more
europepmc   +1 more source

Contribution of α‐synuclein cytopathologies to distinct seeding of misfolded α‐synuclein

open access: yesBrain Pathology, EarlyView.
This study investigated whether brain regions with distinct predominance of α‐synuclein (αSyn) cytopathologies show different αSyn seeding patterns in multiple system atrophy (MSA) and Lewy body disease (LBD), using an interdisciplinary approach. High seeding activity is observed in regions with oligodendrocytic‐predominant αSyn pathology in MSA.
Ain Kim   +4 more
wiley   +1 more source

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes. [PDF]

open access: yesGlia
Ramesh V   +15 more
europepmc   +1 more source

Integration of omics data in the diagnosis and therapy of glioblastoma

open access: yesBrain Pathology, EarlyView.
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller   +3 more
wiley   +1 more source

Profile and Usefulness of Serum Cytokines to Predict Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. [PDF]

open access: yesNeurol Neuroimmunol Neuroinflamm
Villacieros-Álvarez J   +40 more
europepmc   +1 more source

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