Results 211 to 220 of about 63,056 (297)

Transplanted oligodendrocyte progenitor cells improve neurological defects in a rat model of preterm white-matter injury during the sequela phase. [PDF]

Transl Pediatr
Yang H, Liu W, Wang Q, Wang Z, Zhou J, Liu F, Zhang F, Liang J, Qu S, Luan Z.   +9 more
europepmc   +1 more source

Complement dysregulation in human tauopathies

Brain Pathology, EarlyView.
Complement protein and activation product levels were assessed in post‐mortem frontal cortex from three distinct subtypes of Tauopathy: Corticobasal degeneration, globular glial tauopathy, and Pick's disease. Quantification of complement proteins by immunohistochemistry and ELISA showed elevation of key complement proteins (C1q) regulators (FI) and ...
Jacqui Nimmo, Samuel Keat, Louis De Muynck, B. Paul Morgan   +3 more
wiley   +1 more source

CoTF-reg reveals cooperative transcription factors in oligodendrocyte gene regulation using single-cell multi-omics. [PDF]

Commun Biol
Choi JJ, Svaren J, Wang D.
europepmc   +1 more source

Multi‐pronged analysis of pediatric low‐grade glioma and ganglioglioma reveals a unique tumor microenvironment associated with BRAF alterations

Brain Pathology, EarlyView.
A multi pronged analysis approach revealed distinct neoplastic populations in PA and GG. Non‐neoplastic populations in PA showed higher levels of immune mobilizing chemokines in PA compared to GG. Abstract Pediatric low‐grade gliomas (pLGG) comprise 35% of all brain tumors.
Shadi Zahedi, Kent Riemondy, Tian Liu, Andrea M. Griesinger, Andrew M. Donson, April A. Apfelbaum, Rui Fu, Julian Grandvallet Contreras, Michele Crespo, John DeSisto, Madeline M. Groat, Emil Bratbak, Adam Green, Todd C. Hankinson, Michael Handler, Rajeev Vibhakar, Nicholas Willard, Nicholas K. Foreman, Tzu Phang, Jean Mulcahy Levy   +19 more
wiley   +1 more source

Intrinsic retinoic acid synthesis is required for oligodendrocyte progenitor expansion during CNS remyelination. [PDF]

Front Cell Neurosci
Nanescu SE, Wathieu NM, Rosko L, Cha DS, Kumar MN, Olszewski RT, Reger J, Baydyuk M, Dua AN, Krezel W, Zujovic V, Huang JK.   +11 more
europepmc   +1 more source

Contribution of α‐synuclein cytopathologies to distinct seeding of misfolded α‐synuclein

Brain Pathology, EarlyView.
This study investigated whether brain regions with distinct predominance of α‐synuclein (αSyn) cytopathologies show different αSyn seeding patterns in multiple system atrophy (MSA) and Lewy body disease (LBD), using an interdisciplinary approach. High seeding activity is observed in regions with oligodendrocytic‐predominant αSyn pathology in MSA.
Ain Kim, Ivan Martinez‐Valbuena, Krisztina Danics, Shelley L. Forrest, Gabor G. Kovacs   +4 more
wiley   +1 more source

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes. [PDF]

Glia
Ramesh V, Tsoukala E, Kougianou I, Kozic Z, Burr K, Viswanath B, Hampton D, Story D, Reddy BK, Pal R, Dando O, Kind PC, Chattarji S, Selvaraj BT, Chandran S, Zoupi L.   +15 more
europepmc   +1 more source

Integration of omics data in the diagnosis and therapy of glioblastoma

Brain Pathology, EarlyView.
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller, Melanie Schoof, Keith L. Ligon, Ulrich Schüller   +3 more
wiley   +1 more source

Profile and Usefulness of Serum Cytokines to Predict Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. [PDF]

Neurol Neuroimmunol Neuroinflamm
Villacieros-Álvarez J, Espejo C, Arrambide G, Dinoto A, Mulero P, Rubio-Flores L, Nieto P, Alcalá C, Meca-Lallana JE, Millan-Pascual J, Martínez-García P, Bernard-Valnet R, González-Suárez I, Orviz A, Téllez R, Navarro Cantó L, Presas-Rodríguez S, Martínez-Yélamos S, Cuello JP, Alonso A, Morales RP, Bravo GÁ, Benyahya L, Trouillet-Assant S, Dyon-Tafan V, Froment Tilikete C, Ruet A, Bourre B, Deschamps R, Papeix C, Maillart E, Kerschen P, Ayrignac X, Rovira À, Auger C, Audoin B, Montalban X, Tintore M, Mariotto S, Cobo-Calvo A, Marignier R.   +40 more
europepmc   +1 more source