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Adiponectin Fortifies White Matter After Chronic Hypoperfusion-Induced Vascular Dementia. [PDF]

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Miao W   +14 more
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Oligodendrocytes and Myelin

Neurologic Clinics, 1995
Although it was initially thought to be a passive structure, the oligodendrocyte and myelin unit is now considered highly dynamic with many important functions beyond its role in myelination. Inhibitors of neurite growth can be localized to oligodendrocyte and myelin, highlighting the importance of oligodendrocytes in general CNS maintenance and in ...
J A, McLaurin, V W, Yong
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Oligodendrocytic Gliomatosis Cerebri

Acta Neurochirurgica, 2000
We describe a very unusual case of gliomatosis cerebri (GC) with oligodendrocytic differentiation. A 65-year-old man presented with a convulsive seizure. Magnetic resonance (MR) documented diffuse enlargement of cerebral hemispheres, brainstem, and right cerebellar hemisphere.
Tancredi, A   +4 more
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Oligodendrocyte differentiation

2016
In the nervous system, axons transmit information in the form of electrical impulses over long distances. The speed of impulse conduction is enhanced by myelin, a lipid-rich membrane that wraps around axons. Myelin also is required for the long-term health of axons by providing metabolic support.
E S, Mathews, B, Appel
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The Role of Oligodendrocytes and Oligodendrocyte Progenitors in cns Remyelination

1999
Remyelination enables restoration of saltatory conduction and a return of normal function lost during demyelination. Unfortunately, remyelination is often incomplete in the adult human central nervous system (CNS) and this failure of remyelination is one of the main reasons for clinical deficits in demyelinating disease. An understanding of the failure
H S, Keirstead, W F, Blakemore
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Oligodendrocyte origins

Trends in Neurosciences, 1996
In the adult vertebrate CNS, oligodendrocytes are ubiquitously distributed throughout white matter. By contrast, in the embryonic CNS, recent studies suggest that oligodendrocyte precursors arise in a discrete ventral location. Thus, local ventral environmental signals that contribute to the overall patterning of the CNS are likely to influence the ...
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