Results 51 to 60 of about 97,181 (355)
Neurotrauma Reports, 2023 Myelin loss and oligodendrocyte death are well documented in patients with traumatic brain injury (TBI), as well as in experimental animal models after moderate-to-severe TBI.
Alexandra A. Adams +2 more
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Sleep and Oligodendrocyte Functions [PDF]
Current Sleep Medicine Reports, 2015 Transcriptomic studies have revealed that the brains of sleeping and awake animals differ significantly at the molecular level, with hundreds of brain transcripts changing their expression across behavioral states. However, it was unclear how sleep affects specific cells types, such as oligodendrocytes, which make myelin in the healthy brain and in ...
openaire +4 more sources
Scientific Reports, 2017 Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism for many cellular pathways including DNA synthesis, metabolism and maintenance.
Qinjie Weng +9 more
doaj +1 more source
Human induced pluripotent stem cells differentiation into oligodendrocyte progenitors and transplantation in a rat model of optic chiasm demyelination. [PDF]
PLoS ONE, 2011 BACKGROUND: This study aims to differentiate human induced pluripotent stem cells (hiPSCs) into oligodendrocyte precursors and assess their recovery potential in a demyelinated optic chiasm model in rats.
Alireza Pouya +4 more
doaj +1 more source
STAR Protocols, 2023 Summary: Developing an in vitro platform to study neuron-oligodendrocyte interaction, particularly myelination, is essential to understand aberrant myelination in neuropsychiatric and neurodegenerative diseases.
Martina von der Bey +4 more
doaj +1 more source
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
Nature, 2018 Regeneration of myelin is mediated by oligodendrocyte progenitor cells—an abundant stem cell population in the central nervous system (CNS) and the principal source of new myelinating oligodendrocytes. Loss of myelin-producing oligodendrocytes in the CNS
Zita M L Hubler +20 more
semanticscholar +1 more source
Stem Cell Reports, 2018 Summary: Pelizaeus-Merzbacher disease (PMD) is a fatal X-linked disorder caused by loss of myelinating oligodendrocytes and consequent hypomyelination. The underlying cellular and molecular dysfunctions are not fully defined, but therapeutic enhancement ...
Matthew S. Elitt +15 more
doaj +1 more source
Embracing oligodendrocyte diversity in the context of perinatal injury
Neural Regeneration Research, 2017 Emerging evidence is fueling a new appreciation of oligodendrocyte diversity that is overturning the traditional view that oligodendrocytes are a homogenous cell population.
Jessie Newville +2 more
doaj +1 more source
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022 Background Our case explored the spectrum of autoimmune and infectious neurological complications of Coronavirus Disease 2019. In addition, we also reviewed and discussed clinical features, neuroimaging, CSF findings, and outcomes in patients with COVID ...
Mark A. Colantonio +7 more
doaj +1 more source
The adult oligodendrocyte can participate in remyelination
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Remyelination of the CNS is a critical process in restoring function and protecting nerve fibers from degeneration in multiple sclerosis and other demyelinating diseases.
I. Duncan +5 more
semanticscholar +1 more source