Results 51 to 60 of about 92,957 (356)

Sleep and Oligodendrocyte Functions [PDF]

open access: yesCurrent Sleep Medicine Reports, 2015
Transcriptomic studies have revealed that the brains of sleeping and awake animals differ significantly at the molecular level, with hundreds of brain transcripts changing their expression across behavioral states. However, it was unclear how sleep affects specific cells types, such as oligodendrocytes, which make myelin in the healthy brain and in ...
openaire   +4 more sources

Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity

open access: yesScientific Reports, 2017
Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism for many cellular pathways including DNA synthesis, metabolism and maintenance.
Qinjie Weng   +9 more
doaj   +1 more source

Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis and myelitis in COVID-19: a case report and a review of the literature

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Background Our case explored the spectrum of autoimmune and infectious neurological complications of Coronavirus Disease 2019. In addition, we also reviewed and discussed clinical features, neuroimaging, CSF findings, and outcomes in patients with COVID ...
Mark A. Colantonio   +7 more
doaj   +1 more source

Glial Purinergic Signaling in Neurodegeneration

open access: yesFrontiers in Neurology, 2021
Purinergic signaling regulates neuronal and glial cell functions in the healthy CNS. In neurodegenerative diseases, purinergic signaling becomes dysregulated and can affect disease-associated phenotypes of glial cells. In this review, we discuss how cell-
Marie J. Pietrowski   +9 more
doaj   +1 more source

The adult oligodendrocyte can participate in remyelination

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Remyelination of the CNS is a critical process in restoring function and protecting nerve fibers from degeneration in multiple sclerosis and other demyelinating diseases.
I. Duncan   +5 more
semanticscholar   +1 more source

Antigen targeting to dendritic cells: Still a place in future immunotherapy?

open access: yesEuropean Journal of Immunology, Volume 52, Issue 12, Page 1909-1924, December 2022., 2022
Dendritic cell‐based immunotherapy is a promising vaccination strategy to treat infectious diseases, autoimmunity, and cancer. In this review, we present an overview on the current state of antigen targeting approaches via C‐type lectin receptors, with an outlook on future developments and potential for clinical translation.
Patrizia Stoitzner   +4 more
wiley   +1 more source

Embracing oligodendrocyte diversity in the context of perinatal injury

open access: yesNeural Regeneration Research, 2017
Emerging evidence is fueling a new appreciation of oligodendrocyte diversity that is overturning the traditional view that oligodendrocytes are a homogenous cell population.
Jessie Newville   +2 more
doaj   +1 more source

Evolutionary Origins of the Oligodendrocyte Cell Type and Adaptive Myelination

open access: yesFrontiers in Neuroscience, 2021
Oligodendrocytes are multifunctional central nervous system (CNS) glia that are essential for neural function in gnathostomes. The evolutionary origins and specializations of the oligodendrocyte cell type are among the many remaining mysteries in glial ...
Jacob H. Hines
doaj   +1 more source

Oligodendrocyte precursors migrate along vasculature in the developing nervous system

open access: yesScience, 2016
Neuronal migrations follow vascular pathways In the developing brain, various types of cells migrate from their birthplaces to their workplaces. Oligodendrocyte precursors, which develop to form the insulating sheaths that make signal transmission along ...
Hui-hsin Tsai   +10 more
semanticscholar   +1 more source

A role of oligodendrocytes in information processing [PDF]

open access: yesNature Communications, 2020
AbstractMyelinating oligodendrocytes enable fast propagation of action potentials along the ensheathed axons. In addition, oligodendrocytes play diverse non-canonical roles including axonal metabolic support and activity-dependent myelination. An open question remains whether myelination also contributes to information processing in addition to ...
Nicola Strenzke   +17 more
openaire   +8 more sources

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