Results 221 to 230 of about 4,671,022 (267)

Heterogeneity of Oligodendrocytes and Their Precursor Cells

Advances in Experimental Medicine and Biology, 2019
While oligodendrocytes have been thought to be homogenous, a number of reports have indicated evidences of the heterogeneity of oligodendrocytes and their precursor cells, OPCs. Almost a century ago, Del Río Hortega found three and four types of oligodendrocytes with regions where they exist and their morphologies, respectively.
Nobuharu Suzuki, Chikako Hayashi
exaly   +3 more sources

Reciprocal Interactions between Oligodendrocyte Precursor Cells and the Neurovascular Unit in Health and Disease

Cells, 2022
Oligodendrocyte precursor cells (OPCs) are mostly known for their capability to differentiate into oligodendrocytes and myelinate axons. However, they have been observed to frequently interact with cells of the neurovascular unit during development ...
Friederike Pfeiffer
exaly   +2 more sources

A role for Noggin in the development of oligodendrocyte precursor cells

Developmental Biology, 2004
Oligodendrocyte precursor cells (OPCs) can be differentiated in culture into either oligodendrocytes or type-2 astrocytes (2As), depending on the culture conditions. Whereas oligodendrocyte development can occur in the absence of inducing signals, 2A development apparently cannot.
Toru Kondo
exaly   +3 more sources

The oligodendrocyte precursor cell in health and disease

Trends in Neurosciences, 2001
Adult oligodendrocyte precursor cells (OPCs) make up around 5-8% of the glial cell population in the CNS. Their function in the undamaged CNS is largely unknown, but their processes are in contact with nodes of Ranvier and synapses, suggesting a regulatory role at these structures.
J M, Levine, R, Reynolds, J W, Fawcett
openaire   +2 more sources

Isolation and transplantation of oligodendrocyte precursor cells

Journal of the Neurological Sciences, 1984
Newborn DBA/1J mouse neopallium was disaggregated and grown in high cell densities in tissue culture. In culture, the oligodendrocyte cell precursors are recognized as small refractile cells which use astrocyte precursor cells as a substratum. Using metrizamide density gradients, the oligodendrocyte precursor cells were separated from the astroblasts ...
L C, Doering, S, Fedoroff
openaire   +2 more sources

Immunology of oligodendrocyte precursor cells in vivo and in vitro

Journal of Neuroimmunology, 2019
Remyelination following myelin/oligodendrocyte injury in the central nervous system (CNS) is dependent on oligodendrocyte progenitor cells (OPCs) migrating into lesion sites, differentiating into myelinating oligodendrocytes (OLs), and ensheathing axons.
Jack P. Antel, Yun Hsuan Lin, Qiao-Ling Cui, Florian Pernin, Timothy E. Kennedy, Samuel K. Ludwin, Luke M. Healy   +6 more
openaire   +2 more sources

Inhibition of Axon Growth by Oligodendrocyte Precursor Cells

Molecular and Cellular Neuroscience, 2002
The glial scar that forms at the site of injury is thought to be a biochemical and physical barrier to successful regeneration, although the molecules responsible for this barrier function are not well understood. Glia scars contain large numbers of oligodendrocyte precursor cells (OPCs) and these cells can produce several different growth-inhibitory ...
Zhi Jiang, Chen, Yvonne, Ughrin, Joel M, Levine   +2 more
openaire   +2 more sources

Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus

Nature, 2000
Fast excitatory neurotransmission in the central nervous system occurs at specialized synaptic junctions between neurons, where a high concentration of glutamate directly activates receptor channels. Low-affinity AMPA (alpha-amino-3-hydroxy-5-methyl isoxazole propionic acid) and kainate glutamate receptors are also expressed by some glial cells ...
D E, Bergles, J D, Roberts, P, Somogyi, C E, Jahr   +3 more
openaire   +2 more sources