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Oligodendrocyte precursor cells as a therapeutic target for demyelinating diseases
2019The mechanisms regulating differentiation of multipotent oligodendrocyte progenitor cells (OPCs) into mature oligodendrocytes (OLs) are critical to our understanding of myelination and remyelination. Following acute demyelination in the central nervous system, adult OPCs migrate to the injury site, differentiate into OLs and generate new myelin sheaths.
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[The role of oligodendrocyte precursor cells in immunoregulation].
Sheng li xue bao : [Acta physiologica Sinica]Oligodendrocyte precursor cells (OPCs) are recognized as the progenitors responsible for the generation of oligodendrocytes, which play a critical role in myelination of central nervous system. In addition, in demyelinating diseases, such as brain trauma, ischemia, and multiple sclerosis, OPCs are also found in demyelinated regions, but fail to ...
Xiang, Chen, Cheng, He, Peng, Liu
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Oligodendrocyte precursor cells ingest axons in the mouse neocortex
Proceedings of the National Academy of Sciences of the United States of America, 2022Carolyn M. Ott +2 more
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Myelination-independent functions of oligodendrocyte precursor cells in health and disease
Nature Neuroscience, 2023Tim Czopka
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Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord.
Brain, 2002Guus Wolswijk
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Precursor cells of oligodendrocytes and their myelinating potential
Journal of Neuroimmunology, 1998M. Dubois-Dalcq +5 more
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Investigation of Oligodendrocyte Precursor Cell Differentiation by Quantitative Proteomics
Proteomics, 2019Dominic Winter, Volkmar Gieselmann
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Expression of Oligodendrocyte Precursor Cell Markers in Canine Oligodendrogliomas
Veterinary Pathology, 2018James Chambers +2 more
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