Results 101 to 110 of about 17,381 (266)

Viral-induced neurodegenerative disease. [PDF]

, 1999
Viral etiology has been postulated in a variety of neurological diseases in humans, including multiple sclerosis. Several experimental animal models of viral-induced neurodegenerative disease provide insight into potential host- and pathogen-dependent ...
Buchmeier, MJ, Lane, TE
core   +1 more source

Impact of Iron Deficiency on the Growth and Bioelectrical Profile of Different Gut Bacteria

MicrobiologyOpen, Volume 14, Issue 3, June 2025.
This study explores how iron deficiency (ID) affects Escherichia coli (E. coli) and Limosilactobacillus reuteri (L. reuteri) under laboratory conditions induced by the iron chelator 2,2'‐Bipyridyl (BP). L. reuteri showed no significant changes, whereas E.
Elisa Quarta, Marwane Bourqqia‐Ramzi, David Muñoz‐Rodriguez, María Teresa García‐Esteban, Antonio Murciano‐Cespedosa, Álvaro Mateos González, Francisco José Conejero‐Meca, Juan Lombardo‐Hernandez, Jesús Mansilla‐Guardiola, Simona Baroni, Simonetta Geninatti Crich, Stefano Geuna, Luca Munaron, Deborah Chiabrando, Celia Herrera‐Rincon   +14 more
wiley   +1 more source

Construction of a Prognostic Model Using RNA Processing Factor Genes and the Key Role of NSUN6 in Glioma Outcomes

Journal of Cellular and Molecular Medicine, Volume 29, Issue 12, June 2025.
ABSTRACT Glioma is the most common malignant brain tumor and remains associated with a poor prognosis and limited predictive tools. The dysregulation of RNA processing factor genes has been implicated in glioma development, yet their prognostic relevance remains unclear.
Jiarui Chen, Caidi Ying, Zhaowen Gu, Bingrui Zhu, Junjie Wang, Yajun Qian, Haiyan Zheng, Jianming Zhang, Yongjie Wang   +8 more
wiley   +1 more source

13. Trigeminal Neuralgia

Pain Practice, Volume 25, Issue 5, June 2025.
ABSTRACT Introduction Trigeminal neuralgia (TN) is a disorder characterized by recurrent, unilateral brief electric shock‐like pains, abrupt in onset and termination, limited to the distribution of one or more branches of the trigeminal nerve, and triggered by innocuous stimuli.
Bart Jorrit Snel, Steven P. Cohen, Serdar Erdine, Miles R. Day, Jan Van Zundert, Kris Vissers, Jan Willem Kallewaard   +6 more
wiley   +1 more source

Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells [PDF]

, 2015
Although oligodendrocytes constitute a significant proportion of cells in the central nervous system (CNS), little is known about their intermediary metabolism. We have therefore characterised metabolic functions of primary oligodendrocyte precursor cell
Hadera, Mussie G, Kotter, Mark, Porem Amaral, Ana Amaral, Sonnewald, Ursula, Tavares, Joana M   +4 more
core   +4 more sources

Inhibition of the RNA Regulator HuR Mitigates Spinal Cord Injury by Potently Suppressing Post‐Injury Neuroinflammation

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Delivery of SRI‐42127 after spinal cord injury blocks HuR nucleocytoplasmic translocation in microglia and astrocytes to suppress key neuroinflammatory mediators at the site of injury including, IL‐1β, IL‐6, TNF‐α, COX‐2, INOS, and CCL2. In parallel, there is a reduction of peripheral inflammatory responses in the spleen, liver, and circulation.
Mohammed Amir Husain, Reed Smith, Robert E. Sorge, Abdulraheem Kaimari, Ying Si, Ali Z. Hassan, Abhishek Guha, Katherine A. Smith, Christopher P. Cardozo, Jennifer J. DeBerry, Shaida A. Andrabi, L. Burt Nabors, Natalia Filippova, Caroline K. Webb, Peter H. King   +14 more
wiley   +1 more source

Heterogeneity of mature oligodendrocytes in the central nervous system

Neural Regeneration Research
Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.
Chao Weng, Adam M.R. Groh, Moein Yaqubi, Qiao-Ling Cui, Jo Anne Stratton, G. R. Wayne Moore, Jack P. Antel   +6 more
doaj   +1 more source

Cerebrospinal Fluid Analysis in Multiple Sclerosis Diagnosis: An Update [PDF]

, 2019
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) with brain neurodegeneration. MS patients present heterogeneous clinical manifestations in which both genetic and environmental factors are involved ...
Bruna Lo Sasso, Chiara Bellia, Giulia Bivona, Luisa Agnello, Marcello Ciaccio   +4 more
core   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, Volume 8, Issue 5, Page 798-818, May 2025.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats [PDF]

, 2018
Dementia is a major social and economic problem for our aging population. One of the most common of dementia in the elderly is cerebral small vessel disease (SVD). Magnetic resonance scans of SVD patients typically show white matter abnormalities, but we
Atanur, Santosh S., Dominiczak, Anna F., Fornage, Myriam, Graham, Delyth, Harris, Sarah E., Quick, Sophie, Rajani, Rikesh M., Ruigrok, Silvie R., Seshadri, Sudha, Smith, Colin, Verhaaren, Benjamin F. J., Wardlaw, Joanna M., Williams, Anna   +12 more
core   +3 more sources