Results 161 to 170 of about 20,124 (257)

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, EarlyView.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

The Pharmaceutical Industry in 2025: An Analysis of FDA Drug Approvals from the Perspective of Molecules. [PDF]

Molecules
de la Torre BG, Albericio F.
europepmc   +1 more source

CitPH4 Confers Resistance to Citrus Canker by Activating Papain‐Like Cysteine Protease

Plant Biotechnology Journal, EarlyView.
ABSTRACT Citrus canker, a devastating disease caused by Xanthomonas citri subsp. citri (Xcc), poses a significant threat to global citrus production due to the high susceptibility of nearly all commercial citrus cultivars to it. Although transcription factor Citrus PH4 (CitPH4) is well known for regulating fruit acidity, its potential role in plant ...
Tao Yuan, Rongyan Huang, Zhihao Lu, Yujun Zhao, Jingchao Lv, Jiaxian He, Shengjie Lin, Chunyang He, Xukai Liu, Kun Yang, Jialing Fu, Juan Sun, Li Liao, Weikang Zheng, Wang Zhang, Huihui Jia, Yuantao Xu, Xia Wang, Qiang Xu, Fang Ding, Bin Hu   +20 more
wiley   +1 more source

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2-nitroimidazole TAT Conjugate. [PDF]

Drug Dev Res
Mittal S, Jain A, Babu A, Kumar C, Mallia MB.   +4 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

High-Resolution HPLC for Separating Peptide-Oligonucleotide Conjugates. [PDF]

ACS Omega
Naganuma M, Tsuji G, Amiya M, Hirai R, Higuchi Y, Hata N, Nozawa S, Watanabe D, Nakajima T, Demizu Y.   +9 more
europepmc   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Design of a lateral flow assay targeting the conserved NIID_2019-nCoV_N gene region for molecular viral diagnosis. [PDF]

Braz J Med Biol Res
Derin DÇ, Gültekin E.
europepmc   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 43-54, July 2026.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Biomolecule-Photosensitizer Conjugates: A Strategy to Enhance Selectivity and Therapeutic Efficacy in Photodynamic Therapy. [PDF]

Pharmaceuticals (Basel)
Płaskonka DM, Barczyk D, Repetowski P, Warszyńska M, Dąbrowski JM.   +4 more
europepmc   +1 more source