Results 91 to 100 of about 85,666 (256)

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Chlorella vulgaris biorefineries: sustainable biofuels and high‐value carbon capture

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Global reliance on fossil fuels has created urgent economic and environmental challenges, yet large‐scale use of algal biomass remains limited by production costs. Industrial scaling is constrained by inefficient harvesting and the technical challenges of processing recalcitrant cell walls.
Sandyelle Ferreira Alcântara Araújo, Antonio Átila Menezes Ferreira, Lucia Andrea Sindeaux de Oliveira, Dayana Nascimento Dari, Devany Quintela Soares, Eliana Elisa Francelino Mavie, Francisco Leonardo Alves de Moraes Sousa, Jessica Lopes da Silva, João Vitor Gomes de Araújo Silva, Thiago Queiroz da Silva, Ana Karine Portela Vasconcelos, Kelma Maria dos Santos Pires Cavalcante, John Hebert da Silva Felix, José Cleiton Sousa dos Santos   +13 more
wiley   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Multifunctional Design of Solid Polymer Electrolytes: Paving the Way for High‐Performance All‐Solid‐State Batteries

Carbon Energy, EarlyView.
This review provides a comprehensive and systematic overview of the multifunctional design strategies for solid polymer electrolytes (SPEs), a pivotal component for enabling high‐performance all‐solid‐state batteries (ASSBs). It begins with a detailed classification of SPE systems and elaborates on their respective molecular design principles. The work
Bin Man, Yuzhen Zhao, Bo Fu, Yulong Zeng, Yinwen Chen, Qingrui Liu, Wenjing Luo, Xin Li, Xuewei Li, Zikang Zhang, Yun Zheng, Sijie Liu   +11 more
wiley   +1 more source

Simple Guanosine—Amino Acid Hybrids as Low Molecular Weight Hydrogelators

Chemistry – A European Journal, EarlyView.
Unexplored guanosine‐amino acid derivatives act as low molecular weight hydrogelators. Gelation is triggered by K+ ions and pH changes and relies on G‐quadruplex formation. Small changes in the amino acid structure have a strong impact on the mechanical properties of the gels.
Silvia Pieraccini, Samuele Ruffoli, Martina Occhi, Demetra Giuri, Devis Montroni, Claudia Tomasini, Stefano Masiero   +6 more
wiley   +1 more source

Structure Elucidation and Total Synthesis of Granolides A–C: Ethyl‐branched Sesquiterpenes From the Tropical Frog Gephyromantis granulatus

Chemistry – A European Journal, EarlyView.
Males of the tropical frog Gephyromantis granulatus carry unique ethyl‐branched sesquiterpenoid macrolactones in their scent glands. Their structure elucidation was performed by GC/MS, leading to the proposed structures of the granolides. A flexible enantioselective synthesis confirmed the structures and allowed determination of their absolute ...
Johanna Kuhn, Miguel Vences, Stefan Schulz   +2 more
wiley   +1 more source

Hydroprocessing of synthetic kerosene over a non‐sulphided Ni/Al2O3 catalyst: Impact of alcohols and ketones on alkene conversion

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Synthetic jet fuel containing non‐petroleum‐derived kerosene can be produced from synthetic kerosene obtained through processes that include a hydroprocessing step. The potential use of non‐sulphided (reduced) nickel supported on alumina (Ni/Al2O3) was evaluated as an alternative to sulphided catalysts to saturate alkenes in sulphur‐free ...
Garima Chauhan, Felix Link, Cibele Melo Halmenschlager, Arno de Klerk   +3 more
wiley   +1 more source

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

Drug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler, Tobias Veit, Thomas Keller, Volker Auwärter   +3 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Total Synthesis of Sacrolide A and Cytotoxic Evaluation

European Journal of Organic Chemistry, EarlyView.
Isolated from the edible cyanobacterium Aphanothece sacrum, sacrolide A is a highly potent antimicrobial and cytotoxic metabolite. Its total synthesis via a convergent strategy enabled accurate assessment of its effects on liver and colon cells, offering new insights into its bioactivity and potential health risks.
Priyanka Kataria, Kamel Hadj‐Kaddour, Alexis Giraudon, Jawad Belkheir, Alexandre Guy, Thierry Durand, Magali Gary‐Bobo, Camille Oger   +7 more
wiley   +1 more source