Results 101 to 110 of about 165,835 (344)

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]

, 2015
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M, Casas, J-P, Chaturvedi, N, Fatemifar, G, Hingorani, AD, Hughes, AD, Jarvelin, M-R, Kahonen, M, Kangas, AJ, Kettunen, J, Kivimaki, M, Lawlor, DA, Lehtimaki, T, Mantyselka, P, Perola, M, Raitakari, OT, Salomaa, V, Sattar, N, Smith, GD, Soininen, P, Tiainen, M, Tillin, T, Tynkkynen, T, Vanhala, M, Wang, Q, Wurtz, P   +25 more
core   +2 more sources

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids

BMC Medicine, 2012
Cardiovascular diseases and cancers are leading causes of morbidity and mortality. Reducing dietary saturated fat and replacing it with polyunsaturated fat is still the main dietary strategy to prevent cardiovascular diseases, although major flaws have ...
de Lorgeril Michel, Salen Patricia
doaj   +1 more source

Omega-6 and omega-3 fatty acids: Endocannabinoids, genetics and obesity [PDF]

OCL, 2020
The tissue composition of polyunsaturated fatty acids (PUFA) is important to health and depends on both dietary intake and metabolism controlled by genetic polymorphisms that should be taken into consideration in the determination of nutritional requirements, obesity and chronic disease risk.
openaire   +2 more sources

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Importance of a balanced omega 6/omega 3 ratio for the maintenance of health: Nutritional recommendations Importancia del equilibrio del índice omega-6/omega-3 en el mantenimiento de un buen estado de salud: Recomendaciones nutricionales

Nutrición Hospitalaria, 2011
The modification of dietary patterns has led to a change in fatty acid consumption, with an increase in the consumption of ω-6 fatty acids and a markerd reduction in the consumption of ω-3 fatty acids.
C. Gómez Candela, L. M.ª Bermejo López, V. Loria Kohen   +2 more
doaj  

Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production

Microbial Cell Factories, 2012
Omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) provide significant health benefits and this has led to an increased consumption as dietary supplements.
Adarme-Vega T, Lim David K Y, Timmins Matthew, Vernen Felicitas, Li Yan, Schenk Peer M   +5 more
doaj   +1 more source

Interpretation of A Focus Shift From Sarcopenia to Muscle Health in the Asian Working Group for Sarcopenia 2025 Consensus Update

AGING MEDICINE, EarlyView.
The AWGS 2025 consensus shifts focus from diagnosing sarcopenia to promoting muscle health across the lifespan. It simplifies diagnosis to low muscle mass plus low strength, expands screening to middle‐aged adults, and integrates muscle health into the WHO ICOPE framework for early intervention and healthy aging.
Bi Jianghan, Li Jiaojiao, Kang Lin
wiley   +1 more source

​ENRICHING THE CHILD’S DIET WITH POLYENOIC ACIDS AND PREBIOTICS IS THE PATH TO HEALTHY EATING

Педиатрическая фармакология, 2010
The article provides information on healthy eating and discusses the issues in reducing the consumption by the population of essential and functional food components, insufficient adaption of humans to aggressive environmental factors and the need to ...
T.E. Borovik, N.N. Semenova, T.N. Stepanova   +2 more
doaj   +2 more sources

Omega-6:Omega-3 Fatty Acid Ratio and Total Fat Content of the Maternal Diet Alter Offspring Growth and Fat Deposition in the Rat [PDF]

, 2020
Sally A. V. Draycott, Matthew J. Elmes, Beverly S. Mühlhäusler, Simon C. Langley‐Evans   +3 more
openalex   +1 more source