Results 11 to 20 of about 15,940 (198)
Oncolytic viruses for cancer immunotherapy [PDF]
Journal of Hematology & Oncology, 2020 In this review, we discuss the use of oncolytic viruses in cancer immunotherapy treatments in general, with a particular focus on adenoviruses. These serve as a model to elucidate how versatile viruses are, and how they can be used to complement other ...
Otto Hemminki +2 more
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Oncolytic viruses in melanoma [PDF]
Frontiers in Bioscience-Landmark, 2022 Malignant melanoma recurrence remains heterogeneous in presentation, ranging from locoregional disease (i.e., local recurrence, satellites, in transit disease) to distant dermal and visceral metastases. This diverse spectrum of disease requires a personalized approach to management and has resulted in the development of both local (e.g., surgery ...
Camille Robinson +4 more
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Molecular Therapy: Oncolytics, 2019 Measles virus (MeV) is naturally cytolytic by extensive cell-to-cell fusion. Vaccine-derived MeV is toxic for cancer cells and is clinically tested as oncolytic virus.
Jan R.H. Hanauer +3 more
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Global Challenges, 2023 Oncolytic viruses have found a good place in the treatment of cancer. Administering oncolytic viruses directly or by applying genetic changes can be effective in cancer treatment through the lysis of tumor cells and, in some cases, by inducing immune ...
Hai Zou, Xiao‐Zhou Mou, Biao Zhu
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The gamble between oncolytic virus therapy and IFN
Frontiers in Immunology, 2022 Various studies are being conducted on oncolytic virotherapy which one of the mechanisms is mediating interferon (IFN) production by it exerts antitumor effects.
Qingbo Li +10 more
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Pharmaceutics, 2022 Oncolytic virotherapy is a type of nanomedicine with a dual antitumor mechanism. Viruses are engineered to selectively infect and lyse cancer cells directly, leading to the release of soluble antigens which induce systemic antitumor immunity ...
Qing Ji +4 more
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Viruses, 2021 Recent cancer immunotherapy breakthroughs have fundamentally changed oncology and revived the fading hope for a cancer cure. The immune checkpoint inhibitors (ICI) became an indispensable tool for the treatment of many malignant tumors.
Alexander Malogolovkin +5 more
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Recent advances in oncolytic virus therapy for hepatocellular carcinoma
Frontiers in Oncology, 2023 Hepatocellular carcinoma (HCC) is a highly refractory cancer and the fourth leading cause of cancer-related mortality worldwide. Despite the development of a detailed treatment strategy for HCC, the survival rate remains unsatisfactory.
Licheng Zhu +14 more
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Application progress of oncolytic virus combined with immunotherapy in the treatment of malignant tumors [PDF]
Zhongguo aizheng zazhiThe oncolytic virus (OV) therapy utilizes natural or genetically modified viruses to specifically target and infect tumor cells, leading to the destruction of cancer cells by the replication of the virus itself.
LIANG Yingyun, CHEN Jianhua
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