Results 141 to 150 of about 46,704 (314)

Troriluzole attenuates opioid intake, reinforcing efficacy, seeking behaviours, physical dependence and antinociceptive tolerance in rats

British Journal of Pharmacology, Volume 183, Issue 3, Page 505-519, February 2026.
Background and Purpose Riluzole, approved for amyotrophic lateral sclerosis (ALS), has a glutamate‐modulating profile favourable for mitigating opioid addiction. It reduces neuronal glutamate release and enhances glutamate reuptake, offering advantages over agents that only increase glutamate reuptake.
Ewa Galaj, Saadet Inan, Guo‐Hua Bi, Sonita Wiah, George Adamson, Allen B. Reitz, Zheng‐Xiong Xi, Scott M. Rawls   +7 more
wiley   +1 more source

Biased signaling by endogenous opioid peptides. [PDF]

Proc Natl Acad Sci U S A, 2020
Gomes I, Sierra S, Lueptow L, Gupta A, Gouty S, Margolis EB, Cox BM, Devi LA.   +7 more
europepmc   +1 more source

Photoschaltbare Peptide als molekulare Werkzeuge zur Kodierung von Strukturordnung und ‐Unordnung in intrazellulären Aggregaten

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Wir präsentieren ein photoschaltbares Peptid‐Konjugat, das eine isomerabhängige Selbstassemblierung aufweist: Das planare trans‐Isomer bildet geordnete Nanofibrillen, während das nicht‐planare cis‐Isomer ungeordnete Aggregate ausbildet.
Julian Link, Luca Burg, Sarah Chagri, Ha‐Chi Nguyen, David Y.W. Ng, Bart Jan Ravoo, Tanja Weil   +6 more
wiley   +1 more source

Chronic stress differentially alters mRNA expression of opioid peptides and receptors in the dorsal hippocampus of female and male rats. [PDF]

J Comp Neurol, 2021
Johnson MA, Contoreggi NH, Kogan JF, Bryson M, Rubin BR, Gray JD, Kreek MJ, McEwen BS, Milner TA.   +8 more
europepmc   +1 more source

Agonist vs Antagonist Behavior of δ Opioid Peptides Containing Novel Phenylalanine Analogues in Place of Tyr¹

, 2009
Irena Berezowska, Nga N. Chung, Carole Lemieux, Brian C. Wilkes, Peter W. Schiller   +4 more
openalex   +1 more source

Photoswitchable Peptides as Molecular Tools to Encode Structural Order and Disorder in Intracellular Assemblies

Angewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.
We present a photoswitchable peptide conjugate which exhibits isomerism‐dependent self‐assembly: the planar trans‐isomer assembles into well‐ordered nanofibers while the non‐planar cis‐isomer yields disordered aggregates. Our study offers a direct visualization on the effects of structure formation inside living cells.
Julian Link, Luca Burg, Sarah Chagri, Ha‐Chi Nguyen, David Y.W. Ng, Bart Jan Ravoo, Tanja Weil   +6 more
wiley   +1 more source

The Relationship Between Course of Illness and β-Endorphin Plasma Levels in Patients with Schizophrenia

Neuropsychiatric Disease and Treatment, 2020
Małgorzata Urban-Kowalczyk,1 Magdalena Kotlicka-Antczak,1 Dominik Strzelecki,1 Ewa Rudecka,2,3 Janusz Śmigielski4 1Department of Affective and Psychotic Disorders, Medical University of Łódź, Łódź, Poland; 2Babiński Memorial Hospital in Ł ...
Urban-Kowalczyk M, Kotlicka-Antczak M, Strzelecki D, Rudecka E, Śmigielski J   +4 more
doaj  

Endogenous opioid peptides in the descending pain modulatory circuit. [PDF]

Neuropharmacology, 2020
Bagley EE, Ingram SL.
europepmc   +1 more source

Functional differences of iodinated obestatin peptides: in vitro metabolic stability profile [PDF]

, 2010
Peptides are small polymers of 50 amino acids, situated between organic molecules and proteins. Most peptides perform a biochemical-physical function and are therefore considered as potential drugs.
De Spiegeleer, Bart, Van Dorpe, Sylvia, Wallez, Ingeborg   +2 more
core   +1 more source

Post‐tetanic depression of spinal reflexes in the rabbit and the possible involvement of opioid peptides.

, 1984
D. M. Catley, R.W. Clarke, Judith Pascoe
openalex   +2 more sources