Results 41 to 50 of about 21,048 (272)
Perspectives on Endogenous Opioids in Birds
Frontiers in Physiology, 2018 The present review summarizes the state of knowledge of endogenous opioids in birds. Endogenous opioid peptides acts in a neuromodulatory, hormonal and paracrine manner to mediate analgesic and other physiological functions.
Colin G. Scanes +1 more
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Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. [PDF]
PLoS ONE, 2010 BACKGROUND: The opioid system is involved in reward and pain mechanisms and consists in mammals of four receptors and several peptides. The peptides are derived from four prepropeptide genes, PENK, PDYN, PNOC and POMC, encoding enkephalins, dynorphins ...
Görel Sundström +2 more
doaj +1 more source
Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain
Advanced Science, EarlyView.Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang +9 more
wiley +1 more source
Bioactive Peptides in Milk and Milk products, Antimicrobial Properties and Effects on Human Health
Turkish Journal of Agriculture: Food Science and Technology, 2020 In recent years, apart from the nutritional values of foods, functional properties have also gained importance. Bioactive peptides are the fragmentation products of proteins that have a positive effect on human health.
Selda Bulca, Burcu Güvenç
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Hemorphins—From Discovery to Functions and Pharmacology
Molecules, 2021 During the last three decades, a variety of different studies on bioactive peptides that are opioid receptor ligands, have been carried out, with regard to their isolation and identification, as well as their molecular functions in living organisms. Thus,
Przemyslaw Mielczarek +7 more
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Advanced Science, EarlyView.This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun +7 more
wiley +1 more source
Evaluation of in silico approach for prediction of presence of opioid peptides in wheat
Journal of Functional Foods, 2018 Opioid like morphine and codeine are used for the management of pain, but are associated with serious side-effects limiting their use. Wheat gluten proteins were assessed for the presence of opioid peptides on the basis of tyrosine and proline within ...
Swati Garg +3 more
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Pharmaceuticals, 2023 The macrocyclic tetrapeptide CJ-15,208 (cyclo[Phe-D-Pro-Phe-Trp]) and its D-Trp isomer exhibit kappa opioid receptor (KOR) antagonism which prevents stress-induced reinstatement of extinguished cocaine-conditioned place preference. Here, we evaluated the
Kristen H. Scherrer +7 more
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Recent Advances in Bioresorbable Biomedical Applications: From Materials to Devices
Advanced Electronic Materials, EarlyView.Bioresorbable metal, semiconductor, and polymer materials offer new opportunities for skin‐interfaced platforms and implantable electronic devices by eliminating post‐treatment retrieve surgery and electronic waste through dissolution processes in the natural environment.
Do Yun Park +8 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2013 Significant evidence implicates the endogenous opioid system (opioid peptides and receptors) in the mechanisms underlying the psychopharmacological effects of ethanol.
Laura eFont +2 more
doaj +1 more source