Results 31 to 40 of about 512,940 (405)

Examining prevalence and correlates of smoking opioids in British Columbia: opioids are more often smoked than injected

Substance Abuse Treatment, Prevention, and Policy, 2021
Background British Columbia (BC) is in the midst of an opioid overdose crisis. Since 2017, smoking illicit drugs has been the leading mode of drug administration causing overdose death.
Stephanie Parent, Kristi Papamihali, Brittany Graham, Jane A. Buxton   +3 more
doaj   +1 more source

Pilot findings on the real-world performance of xylazine test strips for drug residue testing and the importance of secondary testing methods

Drug and Alcohol Dependence Reports
Background: Xylazine is a sedative found increasingly in the illicit fentanyl supply that can cause hypotension, bradycardia, necrosis and death. This pilot examined the real-world performance of BTNX xylazine test strips (XTS) in drug residue samples ...
Erin Thompson, Jessica Tardif, Merci Ujeneza, Adina Badea, Traci C. Green, Haley McKee, Michelle McKenzie, Ju Nyeong Park   +7 more
doaj   +1 more source

A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer

Pain and Therapy, 2023
Introduction Opioid-induced constipation (OIC) is one of the most common side effects in patients with cancer treated with opioid analgesics. The actual use of laxatives for OIC in Japan remains unelucidated.
Takahiro Higashibata, Takaomi Kessoku, Yasuhide Morioka, Yuichi Koretaka, Hirokazu Mishima, Hidetoshi Shibahara, Yuriko Masuda, Yasushi Ichikawa, Atsushi Nakajima, Takayuki Hisanaga   +9 more
doaj   +1 more source

Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis

British medical journal, 2017
Objectives To identify trends in concurrent use of a benzodiazepine and an opioid and to identify the impact of these trends on admissions to hospital and emergency room visits for opioid overdose.
E. Sun, A. Dixit, K. Humphreys, B. Darnall, L. Baker, S. Mackey   +5 more
semanticscholar   +1 more source

Factors related to the use of opioids as early treatment in patients with knee osteoarthritis

Arthritis Research & Therapy, 2019
Objective To examine factors related to the use of opioids as an early treatment option for knee OA patients Methods Using the Korean nationwide claim database, we selected knee OA patients between 2013 and 2015. Among them, patients without any claim of
Soo-Kyung Cho, Sun-Young Jung, Seongmi Choi, Seul Gi Im, Hyoungyoung Kim, Woo Seok Choi, Eun Jin Jang, Yoon-Kyoung Sung   +7 more
doaj   +1 more source

An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions [PDF]

, 2014
BACKGROUND: In an effort to control non-medical use and/or medical abuse of prescription drugs, particularly prescription opioids, electronic prescription drug monitoring programs (PDMP) have been introduced in North-American countries, Australia and ...
Islam, M. Mofizul, McRae, Ian S.
core   +2 more sources

US National Trends in Pediatric Deaths From Prescription and Illicit Opioids, 1999-2016

JAMA Network Open, 2018
Key Points Question How have US mortality rates for pediatric opioid poisonings changed over the past 2 decades? Findings In this cross-sectional study, 8986 children and adolescents died between 1999 and 2016 from prescription and illicit opioid ...
Julie R. Gaither, V. Shabanova, J. Leventhal   +2 more
semanticscholar   +1 more source

Real-world patterns of opioid therapy initiation in Spain, 2012–2018: A population-based, retrospective cohort study with 957,080 patients and 1,509,488 initiations

Frontiers in Pharmacology, 2022
Introduction: Europe has seen a steady increase in the use of prescription opioids, especially in non-cancer indications. Epidemiological data on the patterns of use of opioids is required to optimize prescription.
Isabel Hurtado, Isabel Hurtado, Celia Robles, Celia Robles, Salvador Peiró, Salvador Peiró, Aníbal García-Sempere, Aníbal García-Sempere, Fran Llopis-Cardona, Fran Llopis-Cardona, Francisco Sánchez-Sáez, Francisco Sánchez-Sáez, Clara Rodríguez-Bernal, Clara Rodríguez-Bernal, Gabriel Sanfélix-Gimeno, Gabriel Sanfélix-Gimeno   +15 more
doaj   +1 more source

An opioid-like system regulating feeding behavior in C. elegans [PDF]

, 2015
Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Artyukhin, Alexander B., Avery, Leon, Cheong, Mi Cheong, You, Yong-Jai   +3 more
core   +3 more sources

Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case–control study

PLoS Medicine, 2017
Background Prescription opioid use is highly associated with risk of opioid-related death, with 1 of every 550 chronic opioid users dying within approximately 2.5 years of their first opioid prescription.
T. Gomes, D. Juurlink, T. Antoniou, M. Mamdani, J. Paterson, W. van den Brink   +5 more
semanticscholar   +1 more source