Results 41 to 50 of about 469,418 (405)
Complete biosynthesis of opioids in yeast
Science, 2015 Toward opioids without poppy fields Producing opioids without having to depend on field-grown poppies would be of great benefit. Synthetic production could potentially produce more-effective drugs with fewer side effects. Now, Galanie et al.
S. Galanie +4 more
semanticscholar +1 more source
Neuroimaging for differential diagnosis of transient neurological attacks
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Background Rapid yet comprehensive neuroimaging protocols are required for patients with suspected acute stroke. However, stroke mimics can account for approximately one in five clinically diagnosed acute ischemic strokes and the rate of thrombolyzed mimics can be as high as 17%.
Ying Wang, Hao Zha
wiley +1 more source
Critical Care, 2019 Background In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be deleterious.
Candelaria de Haro +17 more
doaj +1 more source
Substance Abuse Treatment, Prevention, and Policy, 2021 Background British Columbia (BC) is in the midst of an opioid overdose crisis. Since 2017, smoking illicit drugs has been the leading mode of drug administration causing overdose death.
Stephanie Parent +3 more
doaj +1 more source
US National Trends in Pediatric Deaths From Prescription and Illicit Opioids, 1999-2016
JAMA Network Open, 2018 Key Points Question How have US mortality rates for pediatric opioid poisonings changed over the past 2 decades? Findings In this cross-sectional study, 8986 children and adolescents died between 1999 and 2016 from prescription and illicit opioid ...
Julie R. Gaither +2 more
semanticscholar +1 more source
Pain and Therapy, 2023 Introduction Opioid-induced constipation (OIC) is one of the most common side effects in patients with cancer treated with opioid analgesics. The actual use of laxatives for OIC in Japan remains unelucidated.
Takahiro Higashibata +9 more
doaj +1 more source
Beyond the Syndemic of Opioid Use Disorders and HIV: The Impact of Opioids on Viral Reservoirs
Viruses, 2023 People with HIV are more likely to have opioid use disorder and to be prescribed opioids for chronic pain than the general population; however, the effects of opioids on the immune system and HIV persistence have not been fully elucidated.
Mattia Trunfio +7 more
doaj +1 more source
PLoS Medicine, 2017 Background Prescription opioid use is highly associated with risk of opioid-related death, with 1 of every 550 chronic opioid users dying within approximately 2.5 years of their first opioid prescription.
T. Gomes +5 more
semanticscholar +1 more source
J‐SUPPORT research policy for oral mucositis associated with cancer treatment
Cancer Medicine, Volume 11, Issue 24, Page 4816-4829, December 2022., 2022 Abstract Background Oral mucositis is one of the main areas of research in supportive and palliative care of cancer patients. However, the methodology of prospective clinical trials on oral mucositis has not been established, despite its uniqueness.
Tomoya Yokota +7 more
wiley +1 more source
Pain Physician, 2017 BACKGROUND Opioid use, abuse, and adverse consequences, including death, have escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse, numerous regulations and guidelines for responsible opioid prescribing have been developed
L. Manchikanti +47 more
semanticscholar +1 more source