Results 91 to 100 of about 1,824,086 (180)

Phase coupling between eye and brain pulsations is bidirectional and modulated by the parasympathetic system – An fMREye study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen, Väyrynen Tommi, Huotari Niko, Saarela Ville, Honkamo Marja, Helakari Heta, Järvelä Matti, Korhonen Vesa, Raitamaa Lauri, Kiviniemi Vesa   +9 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Optic Nerve Head Parameters, Retinal Nerve Fiber Layer and Executive Functions in Children with Attention Deficit Hyperactivity Disorder [PDF]

Aim: This study aimed to evaluate the relationship between executive functions and optic nerve head parameters (the disc area, the neuroretinal rim volume and cup-to-disc ratio) and peripapillary retinal nerve fiber layer (pRNFL) in medication-free ...
Ali ÇAKIR, Bedia Sultan ÖNAL, Gonca ÖZYURT, Bahadır UTLU, Gülsüm YİTİK TONKAZ, Berkan ŞAHİN   +5 more
core   +1 more source

Head and neck: Optic Nerve Glioma [PDF]

, 2009
Review on Head and neck: Optic Nerve Glioma, with data on clinics, and the genes ...
Walker, ML, Niazi, T
core   +1 more source

Optimization of Cell Viability Assays for Screening Glioprotective Compounds in Primary Rat Optic Nerve Head Astrocytes

Наукові вісті Національного технічного університету України "Київський політехнічний інститут", 2017
Background. Optic nerve head astrocytes (ONHAs) are the major glia cell type in the non-myelinated optic nerve head where they contribute to extracellular matrix synthesis.
Yuliya A. Naumchuk, Vitaliy B. Maksymenko, Simon Kaja   +2 more
doaj   +1 more source

Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance

Diabetic Medicine, EarlyView.
In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little, Judith Lechner, Giulia De Rossi, Tara Cullen, Jennifer Perais, Eleni Beli, Noemi Lois, Alan W. Stitt   +7 more
wiley   +1 more source

Mechanosensitive release of adenosine 5′‐triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A mechanism for purinergic involvement in chronic strain

, 2014
As adenosine 5'-triphosphate (ATP) released from astrocytes can modulate many neural signaling systems, the triggers and pathways for this ATP release are important.
Macarak, Edward J, Sheffield, Val C, Mitchell, Claire H, Erin E. Coffey, Wennan Lu, Delamere, Nicholas A, Nicholas A. Delamere, Jonathan M. Beckel, Lu, Wennan, Jason C. Lim, Valery I. Shestopalov, Edward J. Macarak, Alan M. Laties, Coffey, Erin E, Shestopalov, Valery I, Jingsheng Xia, Mohammed Shahidullah, Argall, Arthur J, Shahidullah, Mohammed, Zode, Gulab S, Claire H. Mitchell, Beckel, Jonathan M, Lim, Jason C, Xia, Jingsheng, Laties, Alan M, Val C. Sheffield, Gulab S. Zode, Arthur J. Argall   +27 more
core   +1 more source

Mechanosensitive channel inhibition attenuates TGFβ2-induced actin cytoskeletal remodeling and reactivity in mouse optic nerve head astrocytes. [PDF]

Exp Eye Res, 2021
Kirschner A, Strat AN, Yablonski J, Yoo H, Bagué T, Li H, Zhao J, Bollinger KE, Herberg S, Ganapathy PS.   +9 more
europepmc   +1 more source

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor, Rena E. Mullally, Sarah F. McComish, Julia O'Sullivan, Ian Woods, Ingmar Schoen, Massimiliano Garre, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +9 more
wiley   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias, Sedef Kollarik, Michelle Siegel, Christian R. Baumann, Carlos G. Moreira, Daniela Noain   +5 more
wiley   +1 more source