Results 101 to 110 of about 1,824,086 (180)
Characterization of Primary Rat Astrocytes: a Step Towards Optic Nerve Head on a Chip
, 2020 The mechanism by which elevated intraocular pressure (IOP) increases risk of glaucoma remains unknown. A proposed pathway suggests astrocytes sense optic nerve head (ONH) deformation due to increased IOP, triggering their conversion to a reactive ...
Pareek, Priyasha
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, 1986 Using the peroxidase-antiperoxidase staining technique at the light- and electron-microscope levels and two monoclonal antibodies against microtubule-associated protein 2 (MAP2), we found that astrocytes located at the periphery of the rat optic nerve ...
SC Papasozomenos, LI Binder
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Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Approach to the Diagnosis and Differentiation of Glaucomatous and Nonglaucomatous Optic Neuropathies
, 2014 Optic neuropathy denotes degeneration of the retinal ganglion cells with functional and structural impairment of the optic nerve. Functional damage of the optic nerve can be evaluated by checking visual acuity, color vision, pupillary function, and ...
Carmen K. M. Chan +3 more
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Transient ocular hypertension remodels astrocytes through S100B.
PLoS ONEGlaucoma is a series of irreversible and progressive optic nerve degenerations, often accompanied by astrocyte remodeling as the disease progresses, a process that is insufficiently understood.
Weiran Huang +9 more
doaj +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
The Journal of Physiology, EarlyView.Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
BioengineeringAstrocytes, the most common glial cells in the optic nerve head (ONH), provide support and nutrition to retinal ganglion cells. This study aims to investigate the polarization types of astrocytes in the ONH of rats under high intraocular pressure (IOP ...
Bochao Ma, Jifeng Ren, Xiuqing Qian
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A Glial Interplay Regulates Junctional Architecture at the Blood–Brain Barrier of Drosophila
Glia, Volume 75, Issue 1, January 2027.Drosophila perineurial glia are required for septate junction formation at the blood–brain barrier. Glucose transport across the blood–brain barrier is maintained in the absence of perineurial glia. Perineurial glia ablation increases glucose‐only diet sensitivity.
Esteban G. Contreras +7 more
wiley +1 more source
Glia, Volume 74, Issue 12, December 2026.Brain aging alters perineuronal nets and neuroinflammation. 4‐methylumbelliferone reversed these aging‐associated changes. 4‐methylumbelliferone reduced age‐associated cognitive decline. Six months of chronic oral treatment was well tolerated. ABSTRACT Aging‐associated cognitive decline is closely linked to dysregulated glial activity and chronic ...
Anda Cimpean +7 more
wiley +1 more source
, 2020 Optic nerve sheath meningioma is a benign (not malignant) tumor which involves the covering of the optic nerve.
NANOS
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