MedComm, Volume 7, Issue 11, November 2026.Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
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, 2014 Optic nerve head meningocele (ONHM) also known as dural ectasia of the optic nerve sheath is rare. It is reported in patients with neurofibromatosis type 1, but can also be idiopathic.
Musleh A. Algarni; Kenneth Eng; Eman Nasif; Arun N. E. Sundaram
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Corrigendum to "Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization". [PDF]
Oxid Med Cell Longev, 2020 Ju WK +6 more
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Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges
MedComm, Volume 7, Issue 11, November 2026.Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu +7 more
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Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2426-2439, November 2026.Purpose The dependence of the long‐time (tortuosity) limit of the extra‐cellular diffusivity on the intra‐cellular volume fraction is of fundamental importance for microstructure modeling. While such dependencies have been explored for the white matter, the tortuosity limit in gray matter is unknown due to complex cell composition and geometry. Here we
Hong‐Hsi Lee +6 more
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Experimental Physiology, Volume 111, Issue 11, Page 5219-5235, 1 November 2026.Abstract Cerebrospinal fluid (CSF) contributes to brain waste clearance through its coupling with cerebral haemodynamics. Aerobic exercise promotes brain health, but its influence on brain waste clearance remains unclear. This study examined the coupling between CSF and cerebral haemodynamics in endurance athletes. Fifteen young male endurance athletes
Daisuke Hoshi +9 more
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Intraviterious injection approaches to ablate optic nerve astrocytes
, 2019 Astrocytes and oligodendrocytes are the major glial cells present in the central nervous system. While oligodendrocytes play a major role in myelin formation, astrocytes are involved in blood brain barrier formation, neuronal guidance, structural support,
Osei-Bonsu, Nana Adwoa +1 more
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Optic Nerve Head Drusen and Ischemic Optic Neuropathy
, 2002 Ischemic optic neuropathy is a well recognized but rare association with optic nerve head ...
Andrew G. Lee; Cari Lyle; Rosa Tang; Jade Schiffmann; Randy Kardon; Michael Wall; Michael Mabert
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Morphometric analysis of myelinated fibre composition in the optic nerve of adult C57BL and CBA strain mice and (C57BL x CBA) F1 hybrid:a comparison of interstrain variation [PDF]
, 1995 In a study involving 50 optic nerves isolated from 3 different strains of adult male mice, C57BL, CBA and (C57BL x CBA) F1 hybrids, and from adult female CBA strain mice, we observed that the mouse had a lower mean total myelinated nerve fibre count than
Dangata, Y Y +2 more
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Resveratrol Protects Optic Nerve Head Astrocytes from Oxidative Stress-Induced Cell Death by Preventing Caspase-3 Activation, Tau Dephosphorylation at Ser<sup>422</sup> and Formation of Misfolded Protein Aggregates. [PDF]
Cell Mol Neurobiol, 2020 Means JC, Lopez AA, Koulen P.
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