Results 141 to 150 of about 81,886,651 (240)

Signaling via Orexin Receptors : A Pharmacological Study

, 2004
The orexin receptors are a pair of newly discovered G-protein coupled receptors which are activated by the neuropeptides orexins and play a role in sleep/vigilance, apetite/metabolism and neuroendocrine regulation. On a cellular level receptor activation
Holmqvist, Tomas
core  

Suvorexant protects from ocular complications of diabetes in db/db mice. [PDF]

BMJ Open Diabetes Res Care
Sodhi RK, Mahajan N, Abhyankar SD, Bhatwadekar AD.   +3 more
europepmc   +1 more source

Oral Presentation

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

Novel 3‑Heteroaryl Pyrrolidine and Piperidine Compounds as Orexin Receptor Agonists for Treating Sleep Disorders, namely, Narcolepsy and Hypersomnia. [PDF]

ACS Med Chem Lett
Sabnis RW.
europepmc   +1 more source

Orexine [PDF]

, 2017
openaire   +1 more source

Orexin [PDF]

, 2020
openaire   +1 more source

Physiological significance of autocrine orexinergic signaling in extra-hypothalamic tissues. [PDF]

Physiol Rep
Hakizimana JC, Olubiyi MV, Alagbonsi AI.
europepmc   +1 more source

Narcolepsy as an immune-associated hypothalamic encephalopathy: orexin dysfunction and implications for precision sleep medicine. [PDF]

Front Psychiatry
Arias-Carrión O, Ortega-Robles E, Romano P, Pineda C.   +3 more
europepmc   +1 more source

Orexin A [PDF]

, 2019
openaire   +1 more source

Integrative physiology of orexins and orexin receptors.

Integrative physiology of orexins and orexin receptors.
Recent studies have established that the orexin system is a critical regulator of sleep/wake states. Deficiency of orexin signaling results in the sleep disorder narcolepsy-cataplexy in humans, dogs, and rodents. These findings have brought about the possibility of novel therapies for sleep disorders including narcolepsy-cataplexy.
openaire