Results 131 to 140 of about 17,739 (247)

Phenylketonuria [PDF]

, 2004
Genome research is emerging as a new and important tool in biology used to obtain information on gene sequences, genomic interaction, and how genes work in concert to produce the final syndrome or phenotype. Defect in phenylalanine hydroxylase (PAH) gene
Matalon, Reuben, Michals-Matalon, Kimberlee, Surendran, Sankar, Tyring, Stephen K.   +3 more
core  

The role of orexin A in the pathogenesis of ischaemic stroke at high altitude

Experimental Physiology
Orexin offers protection against cerebral ischaemia–reperfusion injury, with high altitude playing a key role in modulating its expression. This study aimed to investigate the effect of high altitude on orexin expression and its pathophysiological ...
Minxia Zhu, Xu Guo, Jing Guo, Zhaojun Zhang, Kexin Zhang, Yaqi Lei, Yuhe Wang, Haoshuang Zhan   +7 more
doaj   +1 more source

Relationship Between Cognitive Impairments and Serum Orexin Levels in Epilepsy Patients

Archives of Epilepsy
Objective: Recent studies on neurodegenerative diseases have indicated that Orexin A plays a role in cognitive impairment. Furthermore, animal studies have demonstrated that Orexin A enhances synaptic plasticity in the hippocampus.
Zeliha Yücel, İrem Fatma Uludağ, Ufuk Şener, Alp Sarıteke, Anıl Baysoy   +4 more
doaj   +1 more source

Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance

, 2009
OBJECTIVE: The hypothalamic control of energy balance is regulated by a complex network of neuropeptide-releasing neurons. Whilst the effect of these neuropeptides on individual aspects of energy homeostasis has been studied, the coordinated response of ...
AC Linthorst, AD Howard, AJ Dunn, AM Wren, AP Goldstone, AS Chen, C Broberger, C Fekete, C Fekete, C J Small, CB Lawrence, CJ Billington, CK Song, CM Edwards, CR Abbott, CR Abbott, D Huszar, D J L Gunner, D Qu, EC Griffiths, GL de, GS Yeo, J Le Magnen, J Le Magnen, J R C Parkinson, JE Morley, JH Strubbe, JJ Hagan, JM Vaughan, JT Clark, K G Murphy, K Hashimoto, K L Smith, KG Mountjoy, KL Smith, L Negri, M A Ghatei, M Egawa, M Egawa, M Harris, M Monda, M Rossi, M Rossi, M Yokota, MM Ollmann, MM Wirth, MS Kim, MS Kim, N M Semjonous, NJ Spiteri, R Hanada, R Poggioli, S R Bloom, S Schuhler, T Hanada, T Sakurai, Y-L Liu   +56 more
core   +1 more source

Effects of Traumatic Brain Injury on the Orexin/Hypocretin System

Neurotrauma Reports
Traumatic Brain Injuries (TBIs) are known to cause a myriad of symptoms in patients. One common symptom after injury is sleep disruptions. One neuropeptide system has been studied repeatedly as a potential cause of sleep disruptions after TBI- the orexin/
Rebecca T. Somach, Miranda M. Lim, Akiva S. Cohen   +2 more
doaj   +1 more source

Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates

Scientific Reports
Tunicates are evolutionary model organisms bridging the gap between vertebrates and invertebrates. A genomic sequence in Ciona intestinalis (CiOX) shows high similarity to vertebrate orexin receptors and protostome allatotropin receptors (ATR).
Maiju K. Rinne, Lauri Urvas, Ilona Mandrika, Dāvids Fridmanis, Darren M. Riddy, Christopher J. Langmead, Jyrki P. Kukkonen, Henri Xhaard   +7 more
doaj   +1 more source

A prolaktin-releasing peptid szerepének vizsgálata a központi idegrendszerben = Role of prolactin-releasing peptide in the central nervous system [PDF]

, 2009
A prolaktin-releasing peptid (PrRP) számos, központi idegrendszeri funkcióját tanulmányoztuk. A tejelválasztásban a PrRP-t nem találtuk fontosnak. Krónikus, de nem akut stressz után a PrRP expresszió megnőtt, az adaptáció során megváltozott szabályozási ...
Tóth, Zsuzsanna, Uhereczky, Gabriella, Várnai, Péter   +2 more
core  

Neurohormonok, neuropeptidek szerepe az idegrendszer és az endokrin rendszer adaptatív működésének szabályozásában = The role of neurohormones and neuropeptides in the regulation of the adaptive function of the neural and endocrine system [PDF]

, 2006
Összefoglalás A vizsgált periodusban a vállalt feladat több neuropeptidnek mint a PACAP 38, orexin A és B endomorphin-1, a MERF, apelin-13, urocortin 1 , 2 és 3, valamint a ghrelinnek vizsgálata olyan idegrendszeri funkciókban mint a tanulás és ...
Gecse, Árpád, Hargitainé Bujdosó, Erika, Jászberényi, Miklós, Kiss, Edina, Kálmánné Adamik, Ágnes, Lepránné Mezei, Zsófia, Pataki, Imre, Telegdy, Gyula, Tiricz, Hilda   +8 more
core  

Research progress of narcolepsy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
The discovery of hypothalamus Hypocretin (Hcrt)/Orexin system and its relationship with narcolepsy is one of the major advances in sleep medicine. Hcrt/Orexin is a significant neurotransmitter in the circadian cycle of arousal.
Fu-long XIAO, Jun ZHANG, Fang HAN
doaj  

Orexin A [PDF]

, 2019
openaire   +1 more source