Results 11 to 20 of about 17,610 (263)

Orexinergic Input to Dopaminergic Neurons of the Human Ventral Tegmental Area [PDF]

open access: yes, 2013
The mesolimbic reward pathway arising from dopaminergic (DA) neurons of the ventral tegmental area (VTA) has been strongly implicated in reward processing and drug abuse.
A Bisetti   +53 more
core   +10 more sources

Orexin A suppresses in vivo GH secretion [PDF]

open access: yesEuropean Journal of Endocrinology, 2004
BACKGROUND/AIMS: Orexins (OXs) are a newly described family of hypothalamic neuropeptides. Based on the distribution of OX neurons and their receptors in the brain, it has been postulated that they could play a role in the regulation of neuroendocrine function. GH secretion is markedly influenced by nutritional status and body weight.
L M, Seoane   +7 more
openaire   +2 more sources

Neuropeptides’ Hypothalamic Regulation of Sleep Control in Children Affected by Functional Non-Retentive Fecal Incontinence

open access: yesBrain Sciences, 2020
Functional non-retentive fecal incontinence (FNRFI) is a common problem in pediatric age. FNRFI is defined as unintended loss of stool in a 4-year-old or older child after organic causes have been excluded.
Vincenzo Monda   +21 more
doaj   +1 more source

Involvement of the Orexinergic System in Cancer: Antitumor Strategies and Future Perspectives

open access: yesApplied Sciences, 2023
Peptides promote the mitogenesis and migration of tumor cells, and cancer cells overexpress peptide receptors. The involvement of the orexinergic system in cancer is reviewed here, including thirteen cancer types (e.g., adrenocortical adenoma, breast ...
Pilar Marcos, Rafael Coveñas
doaj   +1 more source

Orexin-Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine [PDF]

open access: yes, 2015
Release of the neuropeptides corticotropin-releasing factor (CRF) and orexin-A in the ventral tegmental area (VTA) play an important role in stress-induced cocaine-seeking behavior.
Aguinaga, David   +17 more
core   +1 more source

Orexin A activates retrotrapezoid neurons in mice [PDF]

open access: yesRespiratory Physiology & Neurobiology, 2011
The retrotrapezoid nucleus (RTN), located at the ventral surface of the medulla oblongata, contains glutamatergic Phox2b-expressing interneurons that have central respiratory chemoreceptor properties. RTN also operates as a relay for hypothalamic pathways that regulate breathing, one of which probably originates from the orexinergic neurons (Dias et al.
Roman M, Lazarenko   +3 more
openaire   +2 more sources

Orexin-A exerts equivocal role in atherosclerosis process depending on the duration of exposure : in vitro study [PDF]

open access: yes, 2019
Orexin-A is a peptide hormone that plays a crucial role in feeding regulation and energy homeostasis. Diurnal intermittent fasting (DIF) has been found to increase orexin-A plasma levels during fasting hours, while Ramadan fasting which resembles DIF ...
Daskalopoulou, Aphrodite   +9 more
core   +1 more source

Evolution of Orexin Neuropeptide System: Structure and Function

open access: yesFrontiers in Neuroscience, 2020
Orexins are hypothalamic neuropeptides that were initially identified in the rat brain as endogenous ligands for an (previously) orphan G-protein-coupled receptor (GPCR).
Shingo Soya, Takeshi Sakurai
doaj   +1 more source

Presence of orexin A and orexin 1 receptor in the buffalo prostate

open access: yesItalian Journal of Animal Science, 2010
The orexins A and B are two peptides discovered initially in the rat lateral hypothalamus involved in the regulation of some body functions such as food intake, sleep/wake cycle, arterial pressure and heart rate. They interact with two receptors defined &
A. Vittoria, F. Russo, G. Petrosino
doaj   +1 more source

Animals-assisted therapy: A brief review [PDF]

open access: yes, 2018
In rehabilitative setting, the presence of animals can be considered as an important stimulus for verbal and social communication, and for mood regulation.
Cerroni F.   +22 more
core   +1 more source

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