Results 141 to 150 of about 20,577 (234)

Abuse potential assessment of the dual orexin receptor antagonist daridorexant in rats. [PDF]

J Psychopharmacol, 2023
Steiner MA, Toeroek-Schafroth M, Giusepponi ME, Dacome L, Tessari M.   +4 more
europepmc   +1 more source

Comparative pharmacovigilance of non-benzodiazepine receptor agonists versus dual orexin receptor antagonists for insomnia in older adults. [PDF]

Front Pharmacol
Gao S, Feng X, Li Q, Fan J.
europepmc   +1 more source

Wakefulness is governed by GABA and histamine co-transmission [PDF]

, 2015
Brickley, SG, Franks, NP, Houston, CM, Ma, Y, Parker, S, Uygun, DS, Vyssotski, AL, Wisden, W, Yu, X, Yustos, Y, Zecharia, AY, Zhang, Z, Zhiwen, Y   +12 more
core   +1 more source

Effects of Oveporexton, an Orexin Receptor 2-Selective Agonist, on Cognition in Narcolepsy Type 1: A Secondary Analysis of a Randomized Clinical Trial. [PDF]

JAMA Neurol
Lammers GJ, Plazzi G, Mignot E, Pizza F, Dauvilliers Y, Barateau L, Maruff P, Scammell TE, Latzman RD, Naylor M, Olsson T, Stukalin E, Tanaka S, Volfson D, Khachadourian V, Harel BT.   +15 more
europepmc   +1 more source

Estimation of the Orexin Receptor Occupancy From Human Plasma Pharmacokinetics of Vornorexant, a Novel Dual Orexin 1/2 Receptor Antagonist for the Treatment of Insomnia. [PDF]

Pharmacol Res Perspect
Kamigaso S, Konno Y, Hikichi H, Kambe D, Mano Y, Tokumaru Y, Mori H, Yamasaki H, Chino Y, Hachiuma K, Mizuno-Yasuhira A.   +10 more
europepmc   +1 more source

Dual orexin receptor antagonists as promising therapeutics for Alzheimer's disease. [PDF]

NPJ Biol Timing Sleep
Ragsdale SM, Radovich JM, Coiduras II, McCall WV, Grant SC, Lee C, Wilber A.   +6 more
europepmc   +1 more source

A new direction for adjunctive therapy of difficult-to-treat depression: examining the role of orexin receptor antagonists. [PDF]

Eur Arch Psychiatry Clin Neurosci
Thase ME.
europepmc   +1 more source

Presence, distribution and steroidogenic effect of the peptides orexin A and receptor 1 for orexins in the testis of the South American camelid Alpaca (Vicugna pacos). [PDF]

, 2012
ASSISI, LOREDANA, LIGUORI, GIOVANNA, MIRABELLA, NICOLA, Paino S, SQUILLACIOTI, CATERINA, VITTORIA, ALFREDO   +5 more
core   +1 more source

Non-canonical G_q activation by orexin receptor type 2 and lemborexant observed in microsecond molecular dynamics simulations. [PDF]

Sci Rep
Dragan P, Gratio V, Voisin T, Couvineau A, Latek D.   +4 more
europepmc   +1 more source

Successful Methods for Switching from a Benzodiazepine Receptor Agonist to a Dual Orexin Receptor Antagonist for the Treatment of Insomnias. [PDF]

Clin Psychopharmacol Neurosci
Kanahara N, Tachibana M, Oda Y, Hasegawa T, Kimura A, Iyo M.   +5 more
europepmc   +1 more source