Results 221 to 230 of about 20,577 (234)

Downregulation of Orexin Receptor in Hypothalamic Paraventricular Nucleus Decreases Blood Pressure in Obese Zucker Rats

Journal of the American Heart Association, 2019
Jing-Jing Zhou, Xiang-Jian Zhang, De-Pei Li   +2 more
exaly  

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement

Psychopharmacology, 2010
James R Shoblock, Pascal Bonaventure
exaly  

Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology

Bioorganic and Medicinal Chemistry Letters, 2016
Christopher J Winrow, Paul J Coleman
exaly  

Orexins, orexin receptors and cardiovascular regulation during psychological stress

Autonomic Neuroscience, 2013
P. Carrive, B. Dampney, I. Beig
openaire   +1 more source

Pharmacological characterization of MK-6096 – A dual orexin receptor antagonist for insomnia

Neuropharmacology, 2012
Christopher J Winrow, Anthony L Gotter
exaly  

Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders

Bioorganic and Medicinal Chemistry Letters, 2011
Elisabetta Chiarparin
exaly  

Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord

Neuroscience, 2001
exaly  

Identification of highly selective and potent orexin receptor 1 antagonists derived from a dual orexin receptor 1/2 antagonist based on the structural framework of pyrazoylethylbenzamide

Bioorganic and Medicinal Chemistry, 2017
Yunoshin Tamura
exaly  

Chapter V Orexin receptors

2002
Takeshi Sakurai, Guillaume Hervieu, Masashi Yanagisawa   +2 more
openaire   +1 more source

Discovery and development of orexin receptor antagonists as therapeutics for insomnia

British Journal of Pharmacology, 2014
Christopher J Winrow
exaly