Results 201 to 210 of about 59,126 (260)

Editorial: Celebrating 1 year of Frontiers in lab on a chip technologies

Frontiers in Lab on a Chip Technologies
Michael G. Mauk
doaj   +1 more source

Leaf-vein-inspired multi-organ microfluidic chip for modeling breast cancer CTC organotropism. [PDF]

Front Oncol
Liu L, Qu X, Wang Z, Ji C, Ling R, Yan C.   +5 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Organ-on-chip platforms for nanoparticle toxicity and efficacy assessment: Advancing beyond traditional in vitro and in vivo models. [PDF]

Mater Today Bio
Sampaio AR, Maia RF, Ciardulli MC, Santos HA, Sarmento B.   +4 more
europepmc   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut-lung axis. [PDF]

Open Biol
Koceva H, Amiratashani M, Akbarimoghaddam P, Hoffmann B, Zhurgenbayeva G, Gresnigt MS, Marcelino VR, Eggeling C, Figge MT, Amorim MJ, Mosig AS.   +10 more
europepmc   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Core-Shell Hydrogels with Tunable Stiffness for Breast Cancer Tissue Modelling in an Organ-on-Chip System. [PDF]

Gels
Parodi I, Palamà MEF, Di Lisa D, Pastorino L, Lagazzo A, Falleroni F, Aiello M, Fato MM, Scaglione S.   +8 more
europepmc   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Heart-on-a-chip: a revolutionary organ-on-chip platform for cardiovascular disease modeling. [PDF]

J Transl Med
Liu B, Wang S, Ma H, Deng Y, Du J, Zhao Y, Chen Y.   +6 more
europepmc   +1 more source