Results 221 to 230 of about 59,126 (260)

An Organ-on-Chip Platform for Strain-Controlled, Tissue-Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis. [PDF]

Adv Healthc Mater
Mainardi A, Börsch A, Occhetta P, Ivanek R, Ehrbar M, Krattiger L, Oertle P, Loparic M, Martin I, Rasponi M, Barbero A.   +10 more
europepmc   +1 more source

Leveraging femtosecond laser machining for the fabrication of tubular-based Organ-on-Chip systems: modeling cancer metastasis from invasion to intravasation. [PDF]

Mater Today Bio
Jouybar M, Stassen O, Moradi H, Zuo P, den Toonder JMJ.   +4 more
europepmc   +1 more source

Modeling the Effects of Protracted Cosmic Radiation in a Human Organ-on-Chip Platform. [PDF]

Adv Sci (Weinh)
Tavakol DN, Nash TR, Kim Y, Graney PL, Liberman M, Fleischer S, Lock RI, O'Donnell A, Andrews L, Ning D, Yeager K, Harken A, Deoli N, Amundson SA, Garty G, Leong KW, Brenner DJ, Vunjak-Novakovic G.   +17 more
europepmc   +1 more source

Organ-on-chip technology: Opportunities and challenges. [PDF]

Biotechnol Notes
Srivastava SK, Foo GW, Aggarwal N, Chang MW.   +3 more
europepmc   +1 more source

Advances in modeling periodontal host-microbe interactions: insights from organotypic and organ-on-chip systems.

Lab Chip
Makkar H, Sriram G.
europepmc   +1 more source

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Organs on Chips 2013

Lab on a Chip, 2013
Editorial.
Beebe, D.J., Ingber, D.E., Toonder, den, J.M.J.   +2 more
openaire   +2 more sources

Microfluidic organs-on-chips

Nature Biotechnology, 2014
An organ-on-a-chip is a microfluidic cell culture device created with microchip manufacturing methods that contains continuously perfused chambers inhabited by living cells arranged to simulate tissue- and organ-level physiology. By recapitulating the multicellular architectures, tissue-tissue interfaces, physicochemical microenvironments and vascular ...
Sangeeta N, Bhatia, Donald E, Ingber
openaire   +2 more sources

Review on organ on chip

Asian Journal of Pharmacy and Technology, 2021
A multichannel three-dimensional chip of a microfluidic cell culture which enables the simulation of organs is called an “organ on a chip” (OC). With the integration of many other technologies, OCs have been mimicking organs, substituting animal models, and diminishing the time and cost of experiments which is better than the preceding conventional in ...
Rathod Pallavi Vasant, Pagar Swati Appasaheb, Dube Shubhada Bhausaheb, Musmade Deepak Sitaram   +3 more
openaire   +1 more source

Organ-on-chip systems as a model for nanomedicine

Nanoscale, 2023
Organ-on-chip systems recapitulate the form and function of biological organs in highly controlledin vitroconditions and have already been used for testing a variety of nanoparticles. Can they unlock the translational potential of nanomedicine?
Marios Stavrou, Ngan Phung, Jan Grimm, Chrysafis Andreou   +3 more
openaire   +2 more sources

Microfabrication of human organs-on-chips

Nature Protocols, 2013
'Organs-on-chips' are microengineered biomimetic systems containing microfluidic channels lined by living human cells, which replicate key functional units of living organs to reconstitute integrated human organ-level pathophysiology in vitro. These microdevices can be used to test efficacy and toxicity of drugs and chemicals, and to create in vitro ...
Dongeun, Huh, Hyun Jung, Kim, Jacob P, Fraser, Daniel E, Shea, Mohammed, Khan, Anthony, Bahinski, Geraldine A, Hamilton, Donald E, Ingber   +7 more
openaire   +2 more sources