Results 251 to 260 of about 68,048 (303)

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Oral tissue spheroid, organoid, and organ-on chip microphysiological modeling strategies towards enhanced emulation of health and disease. [PDF]

Bioeng Transl Med
Gouveia Z, Özkan A, Giannobile WV, Santerre JP, Wu DT.   +4 more
europepmc   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Microfluidic organ-on-chip systems for periodontal research: advances and future directions. [PDF]

Front Bioeng Biotechnol
Sriram G, Makkar H.
europepmc   +1 more source

Sex-stratified osteochondral organ-on-chip model reveals sex-specific responses to inflammatory stimulation. [PDF]

Mater Today Bio
Conceição F, Meneses J, Lebre F, Becker M, Araújo-Gomes N, Vos R, Ribeiro AR, Alfaro-Moreno E, Leijten J, Moreira Teixeira L.   +9 more
europepmc   +1 more source

State-of-the-art in high throughput organ-on-chip for biotechnology and pharmaceuticals. [PDF]

Clin Exp Reprod Med
Song SH, Jeong S.
europepmc   +1 more source

An Organ-on-Chip Platform for Strain-Controlled, Tissue-Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis. [PDF]

Adv Healthc Mater
Mainardi A, Börsch A, Occhetta P, Ivanek R, Ehrbar M, Krattiger L, Oertle P, Loparic M, Martin I, Rasponi M, Barbero A.   +10 more
europepmc   +1 more source

Leveraging femtosecond laser machining for the fabrication of tubular-based Organ-on-Chip systems: modeling cancer metastasis from invasion to intravasation. [PDF]

Mater Today Bio
Jouybar M, Stassen O, Moradi H, Zuo P, den Toonder JMJ.   +4 more
europepmc   +1 more source

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Organs on Chips 2013

Lab on a Chip, 2013
Editorial.
Beebe, D.J., Ingber, D.E., Toonder, den, J.M.J.   +2 more
openaire   +2 more sources

Microfluidic organs-on-chips

Nature Biotechnology, 2014
An organ-on-a-chip is a microfluidic cell culture device created with microchip manufacturing methods that contains continuously perfused chambers inhabited by living cells arranged to simulate tissue- and organ-level physiology. By recapitulating the multicellular architectures, tissue-tissue interfaces, physicochemical microenvironments and vascular ...
Sangeeta N, Bhatia, Donald E, Ingber
openaire   +2 more sources