Results 61 to 70 of about 5,802,173 (351)

Stem cell culture and differentiation in microfluidic devices toward organ-on-a-chip

open access: yesFuture Science OA, 2017
Microfluidic lab-on-a-chip provides a new platform with unique advantages to mimic complex physiological microenvironments in vivo and has been increasingly exploited to stem cell research.
Jie Zhang   +4 more
semanticscholar   +1 more source

3D organ-on-a-chip: The convergence of microphysiological systems and organoids

open access: yesFrontiers in Cell and Developmental Biology, 2022
Medicine today faces the combined challenge of an increasing number of untreatable diseases and fewer drugs reaching the clinic. While pharmaceutical companies have increased the number of drugs in early development and entering phase I of clinical ...
L. Baptista   +4 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

An improved organ explant culture method reveals stem cell lineage dynamics in the adult Drosophila intestine

open access: yeseLife, 2022
In recent years, live-imaging techniques have been developed for the adult midgut of Drosophila melanogaster that allow temporal characterization of key processes involved in stem cell and tissue homeostasis.
Marco Marchetti   +2 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Tissue culture of oil palm : finding the balance between mass propagation and somaclonal variation [PDF]

open access: yes, 2019
The oil palm (Elaeis guineensis Jacq.) is typically propagated in vitro by indirect somatic embryogenesis, a process in which somatic cells of an explant of choice are, via an intermediate phase of callus growth, induced to differentiate into somatic ...
Inzé, Dirk, Maene, Ludo, Weckx, Sylvie
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Effect of Exogenous Plant Growth Regulators on Antioxidant Defense in Zucchini Cotyledons Under Different Light Regimes

open access: yesAgriculture
Epigeal cotyledons with excised embryonic axes are often used as a model system to study the processes of cell division and expansion. These processes are regulated by diverse phytohormones and signaling molecules.
Asya Petrova   +3 more
doaj   +1 more source

Evaluation of the effects of titanium dioxide nanoparticles on cultured Rana catesbeiana tailfin tissue

open access: yesFrontiers in Genetics, 2013
Nanoparticles (NPs), materials that have one dimension less than 100 nm, are used in manufacturing, health and food products, and consumer products including cosmetics, clothing and household appliances.
S. Austin eHammond   +2 more
doaj   +1 more source

Fetal Skin Organ Culture

open access: yesJournal of Investigative Surgery, 1990
The fetal response to cutaneous injury has been investigated in a variety of models; most have studied the differences between fetal and adult healing mechanisms in vivo and in cell culture. Further disclosure of the cellular and biochemical events requires a model that can be manipulated to study single factors influencing fetal tissue repair without ...
J H, Haynes   +4 more
openaire   +2 more sources

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