Results 121 to 130 of about 307,002 (301)
Advanced Materials, EarlyView.Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Turnover of organelles by autophagy in yeast
, 2009 Efficient detection and removal of superfluous or damaged organelles are crucial to maintain cellular homeostasis and to assure cell survival. Growing evidence shows that organelles or parts of them can be removed by selective subtypes of otherwise ...
Farre, Jean-Claude +3 more
core +1 more source
Advanced Materials Interfaces, EarlyView.PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi +9 more
wiley +1 more source
Editorial: Organelles Relationships and Interactions: A Cancer Perspective
Frontiers in Cell and Developmental Biology, 2021 Simone Patergnani +3 more
doaj +1 more source
Dynamic regulation of endosymbiotic organelles by ubiquitination.
, 2013 Recent work has revealed that mitochondria and chloroplasts are subject to direct control by the ubiquitin-proteasome system (UPS). Ubiquitin E3 ligases are present at the outer membrane of both organelles where they mediate ubiquitination and turnover ...
Ling, Q, Jarvis, Paul, Jarvis, P
core +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
Advanced Science, EarlyView.A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Cellular organelles (Ultrastructure and function)
, 2011 Fundamental knowledge on the ultrastructure and function of cellular organelles and structures of animal and plant cell is provided. Useful information required for appropriate photo interpretation of transmisson electron microscopy (TEM) images of ...
Lopes, Orlando
core
Femtosecond laser manipulation of subcellular organelles in living cells [PDF]
European Conferences on Biomedical Optics 2005, 2005, Munich, GermanyWataru Watanabe, Tomoko Shimada, Kazuyoshi Itoh, Sachihiro Matsunaga, Kiichi Fukui, "Femtosecond laser manipulation of subcellular organelles in living cells," Proc.
Matsunaga, Sachihiro +4 more
core +1 more source