Results 41 to 50 of about 1,532,406 (293)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Organisational Citizenship Behaviour and Turnover Intention: The Role of Organisational Justice, Commitment and Perceived Support [PDF]

open access: yes, 2013
Attracting and retaining committed teachers who are willing to perform extra-role activities that go above and beyond their prescribed jobs can be a key asset to an academic institution.
Esop, Michael
core  

Influence of Social Skills on Organisational Performance in Public Universities in Kenya’s Western Region: The Moderating Role of Organisational Justice

open access: yesEastern African Journal of Humanities and Social Sciences
This research aimed to assess the impact of social skills on organisational performance and to identify the moderating effect of organisational justice on the relationship between leadership emotional intelligence and organisational performance in ...
Priscah Avion Luchivisi   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

EFFECTS OF ORGANISATIONAL JUSTICE AND JOB STRESSORS ONEMPLOYEE HEALTH: A MULTILEVEL MEDIATION APPROACH

open access: yesInternational Journal of Management Studies
Research to date, has found that organisational justice enhances different kinds of work outcomes in an organisation. However, while most studies have investigated the effect of organisational justice on employees’ outcomes via several mediational ...
Vanisa Karupaiah   +2 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Justice must be seen to be done: organisational justice and the headscarf and burqa laws in France [PDF]

open access: yes, 2012
This article discusses the 'affair of the headscarf' in France in 1989, its aftermath, the 2004 enactment of a secularism law forbidding students to wear visible religious signs in public schools, and the 2010 adoption of a law prohibiting the wearing of
Jones, Nicky
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Enforceable undertakings: Perceptions of organisational justice [PDF]

open access: yes, 2015
In this thesis the use of enforceable undertakings is examined as a sanction for a breach in work, health and safety legislation through the lens of organisational justice.
Jess, Gabrielle M.
core  

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