Results 21 to 30 of about 78,797 (204)
The Algorithmic Origins of Life [PDF]
, 2012 Although it has been notoriously difficult to pin down precisely what it is that makes life so distinctive and remarkable, there is general agreement that its informational aspect is one key property, perhaps the key property.
Cairns-Smith AG +20 more
core +1 more source
DRUG REPURPOSING—Overcoming the translational hurdles to clinical use
Pharmacology Research & Perspectives, 2019 Drug repurposing is a methodology for identifying new uses for approved or investigational drugs outside the scope of the original medical indication.
Jennifer H. Martin, N. Bowden
semanticscholar +1 more source
Shedding Light on the Cell Biology of the Predatory Bacterium Bdellovibrio bacteriovorus
Frontiers in Microbiology, 2020 Bdellovibrio bacteriovorus is a predatory bacterium that feeds upon and proliferates inside other Gram-negative bacteria. Upon entry into the periplasmic space of the prey envelope, B.
G. Laloux
semanticscholar +1 more source
iScience, 2023 Summary: We present a study on the nuclear export efficiency and time of pre-ribosomal subunits in live mammalian cells, using high-speed single-molecule tracking and single-molecule fluorescence resonance energy transfer techniques.
Samuel L. Junod +5 more
doaj +1 more source
A Synthesis Concerning Conservation and Divergence of Cell Types across Epithelia.
Cold Spring Harbor Perspectives in Biology, 2020 Advances in single-cell RNA-seq (scRNA-seq) and computational analysis have enabled the systematic interrogation of the cellular composition of tissues.
Daniel T. Montoro +4 more
semanticscholar +1 more source
Current Medicine Research and Practice, 2022 Monkeypox virus (MPXV) infection has lately emerged as a new public health problem across 100 countries. Surging cases of MPXV infection in non-endemic countries prompted the World Health Organization to declare it a public health emergency in July 2022.
D. Kaul, K. Yadav, A. Bansal
semanticscholar +1 more source
Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core +1 more source
iScience, 2023 Summary: PARP1 contributes to genome architecture and DNA damage repair through its dynamic association with chromatin. PARP1 and PARP2 (PARP1/2) recognize damaged DNA and recruit the DNA repair machinery.
Jyothi Mahadevan +6 more
doaj +1 more source
iScience, 2022 Summary: Podosomes, an important actin-based adhesive architecture, play critical roles in cell migration and matrix invasiveness. Here, we elucidate the ultrastructural organization and regulation of podosome clusters in primary macrophages.
Fen Hu +10 more
doaj +1 more source
Understanding Multicellularity: The Functional Organization of the Intercellular Space [PDF]
, 2019 The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration,
Bich, Leonardo +2 more
core +11 more sources