Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Organizational Support as Perceived by Staff Nurses and Its Relation to Their Autonomy
Context: Nurses need support at all levels in the organization. When staff nurses perceive organizational support, this can promote their sense of well-being, raise positive work behaviors and enhance their autonomy in patient care and unit operational ...
Ehsan S. S. Saad, Samah M. Elsayed
doaj +1 more source
A Knowledge‐Based Approach for Understanding and Managing Additive Manufacturing Data
Additive manufacturing processes generate a large amount of data. Effectively managing, understanding, and retrieving information from this data remains a major challenge. Therefore, we propose an ontology‐based approach to integrate heterogeneous data, enable semantic queries, and support decision‐making.
Mina Abd Nikooie Pour +5 more
wiley +1 more source
大學圖書館館員領導者與成員交換關係、工作自主性及組織公民行為之關係模式探析 A Study of the Relationship among Leader-Member Exchange, Job Autonomy and Organizational Citizenship Behavior of the University Librarians in Taiwan [PDF]
大學圖書館領導者需要激勵館員表現組織公民行為,以提升圖書館組織績效與服務品質。本研究採用問卷調查方式,運用結構方程模式(structural equation modeling, SEM),驗證大學圖書館館員之領導者與成員交換關係(LMX)、工作自主性及組織公民行為之關係,研究結果顯示:(1)館員認知的領導者與成員交換關係(LMX)程度愈高,其工作自主性程度愈高;(2)館員認知的工作自主性程度愈高,其組織公民行為程度愈高;(3)工作自主性對領導者與成員交換關係(LMX)及組織公民行為之關係 ...
Yu-Ping Peng
doaj +1 more source
INTRAPRENEURSHIP AUTONOMY AND ORGANIZATIONAL ADAPTABILITY
This study delves into the dynamic relationship between intrapreneurial innovativeness and organizational sustainability, recognizing the critical role of product, process, and market innovations in fostering lasting value. Through an exploration of literature and empirical evidence, this research seeks to elucidate how organizations can effectively ...
Oluchi Vincent Ogbumgbada +1 more
openaire +2 more sources
An Empirical Investigation of Organizational Readiness towards Hospital Autonomy
Background: We aimed to investigate Tehran’s University of Medical Sciences (TUMS) affiliated hospitals organizational readiness toward implementing the ‘Autonomous Hospitals’ program as a change initiative from a managerial perspective in 2020. Methods: A census covering all eligible managers working in TUMS affiliated hospitals, Tehran, Iran (350 ...
Alaei Kalajahi, Riaz +4 more
openaire +3 more sources
A Lightweight Procedural Layer for Hybrid Experimental–Computational Workflows in Materials Science
We unveil a prototype hybrid‐workflow framework that fuses automatedcomputation with hands‐on experiments. Built atop pyiron, a lightweight, parameterized layer translates procedure descriptions into executable manual steps, syncing instrument settings, human interventions, and data capture in real‐time today.
Steffen Brinckmann +8 more
wiley +1 more source
Background: Although work absenteeism is in the focus of occupational health, longitudinal studies on organizational absenteeism records in hospital work are lacking.
Maria U. Kottwitz +4 more
doaj +1 more source

